Biology Department Biology Department  

Scanning Transmission Electron Microscopy Facility


  • Makhov A.M., Sen A., Yu X., Simon M.N., Griffith J.D., and Egelman E.H.
    The Bipolar Filaments Formed by Herpes Simplex Virus Type 1 SSB/Recombination Protein (ICP8) Suggest a Mechanism for DNA Annealing.
    J Mol Biol., 386(2):273-9 (2009).  PubMed
  • Ohi M.D., Ren L., Wall J.S., Gould K.L., and Walz T.
    Structural characterization of the fission yeast U5.U2/U6 spliceosome complex.
    Proc Natl Acad Sci USA., 104(9):3195-200 (2007).  PubMedFull Text
  • Ohi M.D., Feoktistova A., Ren L., Yip C., Cheng Y., Chen J.S., Yoon H.J., Wall J.S., Huang Z., Penczek P.A., Gould K.L., and Walz T.
    Structural organization of the anaphase-promoting complex bound to the mitotic activator slp1.
    Molecular Cell, 28(5):871-85 (2007).  PubMed
  • Yakubovskaya E., Lukin M., Chen Z., Berriman J., Wall J.S., Kobayashi R., Kisker C., and Bogenhagen D.F.
    The EM structure of human DNA polymerase gamma reveals a localized contact between the catalytic and accessory subunits.
    EMBO J., 2007 Aug 30; [Epub ahead of print]  PubMed  
  • Francis N.J., Kingston R.E., and Woodcock C.L.
    Chromatin compaction by a polycomb group protein complex.
    Science, 306:1574-1577 (2004).  PubMedFull Text
  • Smith C.L., Horowitz-Scherer R., Flanagan J.F., Woodcock C.L., and Peterson C.L.
    Structural analysis of the yeast SWI/SNF chromatin remodeling complex.
    Nat Struct Biol., 10(2):141-145 (2003).  PubMedFull Text
  • Citovsky V., Guralnick B., Simon M.N., and Wall J.S.
    The molecular structure of agrobacterium VirE2 single stranded DNA complexes involved in nuclear import.
    J. Mol. Biol., 271:718-27 (1997).  PubMed
  • Yu X., West S.C., and Egelman E.H.
    Structure and subunit composition of RuvAB-Holliday junction complex.
    J. Mol. Biol., 266(2):217-222 (1997).  PubMed
  • Blackwell L.J., Borowiec J.A., and Mastrangelo I.A.
    Single stranded binding alters human replication protein A structure and facilitates interaction with DNA dependent protein kinase.
    Mol. Cell. Biol., 16:4798-4807 (1996).
  • Stasiak A., Tsaneva I.R., West S.C., Benson C.J.B., Yu X., and Egelman EH.
    The Eschericia coli RuvB branch migration protein forms double hexameric rings around DNA.
    Proc. Natl. Acad. Sci. USA., 91:7618-7622 (1994).
  • Stenger J.E., Tegtmeyer P., Mayr G.A., Reed M., Wang Y., Wang P., Hough P.V.C., and Mastrangelo I.A.
    p53 oligomerization and DNA looping are linked with transcriptional activation.
    EMBO. J., 13(24):6011-6020 (1994).  PubMed
  • Tumminia S.J., Hellmann W., Wall J.S. and Boublik M.
    Visualization of the protein-nucleic acid interactions involved in the in vitro assembly of the Escherichia coli 50S ribosomal subunit.
    J. Mol. Biol., 235:1239-1250 (1994).  PubMed
  • Mastrangelo I.A., Held P.G., Dailey L., Wall J.S., Hough P.V.C., Heintz N., and Heintz N.H.
    RIP60 dimers and multiples of dimers assemble link structures at an origin of bi-directional replication in the dihydrofolate reductase amplicon of Chinese hamster ovary cells.
    J. Mol. Biol., 232:766-778 (1993).
  • Yu X., and Egelman E.H.
    The LexA repressor binds within the deep helical groove of the activated RecA filament.
    J. Mol. Biol., 231:29-40 (1993).  PubMed
  • Tumminia S.J., Hellmann W., Wall J.S. and Boublik M.
    Image analysis of Artemia salina ribosomes by scanning transmission electron microscopy.
    J. Struc. Biol., 109:109-115 (1992).  PubMed
  • Turnquist S., Simon M., Egelman E., and Anderson D.
    Supercoiled DNA wraps around the bacteriophage Phi 29 head tail connector.
    PNAS, 89(21):10479-10483 (1992).  PubMed
  • Yu X. and Egelman E.H.
    Structural data suggest that the active and inactive forms of Rec A filament are not simply interconvertible.
    J. Mol. Biol., 227:334-346 (1992).
  • Mandiyan V., Tumminia S., Wall J.S., Hainfeld J.F., and Boublik M.
    Assembly of the Escherichia coli 30S ribosomal subunit reveals protein dependent folding of the 16S rRNA domains.
    PNAS, 88(18):8174-8178 (1991).  PubMed
  • Mastrangelo I.A., Courey A.J., Wall J.S., Jackson S.P., and Hough P.V.C.
    DNA looping and Sp1 multimer links: a mechanism for transcriptional synergism and enhancement.
    PNAS, 88(13):5670-5674 (1991).  PubMed
  • Tumminia S.J., Mandiyan V., Wall J.S. and Boublik M.
    Heterogeneity of Escherichia coli ribosomes established by scanning transmission electron microscopy.
    Biochimie, 73(7-8):919-925 (1991).  PubMed
  • Mandiyan V., Tumminia S., Wall J.S., Hainfeld J.F. and Boublik M.
    Visualization of ion-dependent conformational changes in E. coli 23S ribosomal RNA by scanning transmission electron microscopy.
    Arch. Biochem. Biophys., 276:299-304 (1990).
  • Mandiyan V., Tumminia S., Wall J.S., Hainfeld J.F., and Boublik M.
    Protein-induced conformational changes in 16S rRNA during the initial assembly steps of the Escherichia coli 30S ribosomal subunit.
    J. Mol. Biol., 210:323-336 (1990).
  • Mastrangelo I.A., Hough P.V.C., Wall J.S., Dodson M., Dean F.B. and Hurwitz J.
    ATP dependent assembly of double hexamers of SV40 T antigen at the viral origin of DNA replication.
    Nature, 338(6217):658-662 (1989).  PubMed
  • Mandiyan V., Hainfeld J.F., Wall J.S., and Boublik M.
    Conformation analysis of 16S ribosomal RNA from Escherichia coli by scanning transmission electron microscopy.
    FEBS Lett., 236(2):340-344 (1988). PubMed
  • Gerchman S.E., and Ramakrishnan V.
    Chromatin higher order structure studied by neutron scattering and scanning transmission electron microscopy.
    PNAS, 84(22):7802-7806 (1987). PubMed
  • Hough P.V.C., Mastrangelo I.A., Wall J.S., Hainfeld J.F., Sawadogo M., and Roeder R.G.
    The gene specific initiation factor USF (upstream stimulatory factor) bound at the adenovirus type 2 major late promoter: mass and three dimensional structure.
    PNAS USA, 84(14):4826-4830 (1987).  PubMed
  • Boublik M., Oostergetel G.T., Joy D.C., Wall J.S., Hainfeld J.F., Frankland B., and Ottensmeyer F.P.
    In situ localization of ribonucleic acids in biological specimens by electron energy loss spectroscopy.
    Second Colloquium in Biological Sciences, C. D. Burrell and F. L. Strand, eds., Vol. 463, pp. 168 170, New York Academy of Sciences, New York (1986).
  • Boublik M., Oostergetel G.T., Wall J.S., Hainfeld J.F., Radermacher M., Wagenknecht T., Verschoor A., and Frank J.
    Structure of ribosomes and their components by advanced techniques of electron microscopy and computer image analysis.
    Structure, Function and Genetics of Ribosomes, B. Hardesty and Kramer, eds., Springer Verlag, New York, pp. 68 86 (1986).
  • Wooley J., Chung S.Y., Wall J.S., and LeStourgeon W.
    Architecture of pre messenger, nuclear ribonucleoprotein monoparticles.
    Biophys. J., 49:17-19 (1986).
  • Hough P.V.C., Mastrangelo I.A., Wall J.S., Hainfeld J.F., Wilson V.G., Ryder K., and Tegtmeyer P.
    STEM footprints and bound mass distributions for DNA control proteins.
    Biotechnology, 3:549-553 (1985).
  • Mastrangelo I.A., Hough P.V.C., Wilson V.G., Wall J.S., Hainfeld J.F., and Tegtmeyer P.
    Monomers through trimers of large tumor antigen bind in region I and monomers through tetramers bind in region II of simian virus 40 origin of replication DNA as stable structures in solution.
    PNAS USA, 82(11):3626-3630 (1985).  PubMed
  • Oostergetel G., Wall J.S., Hainfeld J.F. and Boublik M.
    Quantitative structural analysis of eukaryotic ribosomal RNAs by scanning transmission electron microscopy.
    PNAS USA, 82:5598-5602 (1985).
  • Ryder K., Vakalopoulou E., Mertz R., Mastrangelo I., Hough P., Tegtmeyer P., and Fanning E.
    Seventeen base pairs of region I encode a novel tripartite binding signal for SV40 T antigen.
    Cell, 42(2):539-548 (1985).  PubMed
  • Woodcock C.L.F., and Frank J.
    Nucleosome mass distribution using image averaging.
    J. Ultrastr. Res., 89(3):295-302 (1984).  PubMed
  • Woodcock C.L.F., Frado L.L.Y., and Rattner J.B.
    The higher order structure of chromatin: evidence for a helical ribbon arrangement.
    J. Cell. Biol, 99(1):42-52 (1984).  PubMed
  • Boublik M., Robakis N., Hellmann W., and Wall J.S.
    Electron microscopic study of free and ribosome bound rRNAs from E. coli.
    Eur. J. Cell. Biol., 27(2):177-184 (1982).  PubMed
  • Hough P.V.C., Mastrangelo I.A., Wall J.S., Hainfeld J.F., Simon M.N., and Manley J.L.
    DNA protein complexes spread on N2 discharged carbon film and characterized by molecular weight and its projected distribution. Nucleosome formation in an in vitro transcription system.
    J. Mol. Biol., 160:375-386 (1982).
  • Woodcock C.L., Frado L.L., and Wall J.S.
    Composition of native and reconstituted chromatin particles: direct mass determination by scanning transmission electron microscopy.
    PNAS USA, 77:4818-4822 (1980).  PubMed  Full Text

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Last Modified: May 6, 2009
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