General Information

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Andrew Gifford

Research Interests

  • Novel techniques for the radiochemical labeling of biomolecules for systems biology.
  • Uptake and distribution studies on radiofluorinated sugar analogues.
  • Autoradiography and PET imaging.

Selected Publications

  • Best M., Gifford A.N., Kim S.W., Babst B., Piel M., Rosch F. and Fowler J.S.
    Rapid radiosynthesis of [11C] and [14C]azelaic, suberic and sebacic acids for in vivo mechanistic studies of systemic acquired resistance in plants.
    J. Labelled Comp. Radiopharm., 55(1):39-43 (2012). Web Link
  • Gifford A.N., Bennett C.V., and Fowler J.S.
    Radiosynthesis of the Fluorinated Sucrose Analogue, 1’-[18F]Fluoro-1’-deoxysucrose.
    J. Labelled Comp. Radiopharm., 55(12):441-446 (2012). Web Link
  • Gifford A.N., Kuschel S., Shea C., and Fowler J.S.
    Polymer-supported organotin reagent for prosthetic group labeling of biological macromolecules with radioiodine.
    Bioconjugate Chemistry, 22(3):406-412 (2011). PubMed
  • Gifford A.N., Espaillat M.P. and Gatley S.J.
    Biodistribution of radiolabeled ethanol in rodents.
    Drug Metab. Dispos., 36(9):1853-1858 (2008).  PubMed
  • Tovar-Salazar A., Dhawan J., Lovejoy A., Liu Q.A. and Gifford A.N.
    Preparation of radioiodinated peptide nucleic acids with high specific activity.
    Anal. Biochem., 360(1):92-98 (2007).  PubMed
  • Dhawan J., Deng H., Gatley S.J., Makriyannis A., Akinfeleye T., Bruneus M., DiMaio A.A. and Gifford A.N.
    Evaluation of the in vivo receptor occupancy for the behavioral effects of cannabinoids using a radiolabeled cannabinoid receptor agonist, R-[125/131I]AM2233.
    Synapse, 60(2):93-101 (2006).  PubMed
  • Glaser S.T., Gatley S.J. and Gifford A.N.
    Ex-vivo imaging of fatty acid amide hydrolase (FAAH) activity and its inhibition in the mouse brain.
    J. Pharmacol. Exp. Ther., 316(3):1088-1097 (2006).  PubMed
  • Deng H., Gifford A.N., Zvonok A.M., Cui G., Li X., Fan P., Deschamps J.R., Flippen-Anderson J.L., Gatley S.J. and Makriyannis A.
    Potent cannabinergic indole analogues as radioiodinatable brain imaging agents for the CB1 cannabinoid receptor.
    J. Med. Chem., 48(20):6386-6392 (2005).  PubMed