Jean Logan

Research Interests

• Image analysis techniques; kinetic analysis of PET data
• See Also Radiotracer Chemistry and Neuroimaging

Selected Publications

• Logan J., Alexoff D., and Fowler J.S.
  The use of alternative forms of graphical analysis to balance bias and precision in PET images.
  J. Cereb. Blood Flow Metab., 31(2):535-546 (2011).  PubMed
• Wang G.-J., Geliebter A., Volkow N.D., Telang F.W., Logan J., Jayne M.C., Galanti K., Selig P.A., Han H., Zhu W., Wong C.T., and Fowler J.S.
  Enhanced Striatal Dopamine Release During Food Stimulation in Binge Eating Disorder.
  OBESITY (Silver Spring). 2011 Feb 24.  PubMed
• Biegon A., Kim S.W., Alexoff D.L., Jayne M., Carter P., Hubbard B., King P., Logan J., Muench L., Pareto D., Schlyer D., Shea C., Telang F., Wang G.J., Xu Y., and Fowler J.S.
  Unique distribution of aromatase in the human brain: in vivo studies with PET and [N-methyl-11C]vorozole.
  Synapse, 64(11):801-807 (2010).  PubMed
• Biegon A., Kim S.W, Logan J., Hooker J.M., Muench L., and Fowler J.S.
  Nicotine Blocks Brain Estrogen Synthase (Aromatase): In Vivo Positron Emission Tomography Studies in Female Baboons.
  Biol. Psychiatry, Feb 24 (2010) [Epub ahead of print].  PubMed
• Logan J., Biegon A., Kim S.W., Alexoff D., and Fowler, J.S.
  Quantitating aromatase in the human brain with PET and [N-methyl-11C]vorozole([11C]VOR)
  CONFERENCE: 8th International Symposium on Functional Neuroreceptor Mapping of the Living Brain (NRM2010), University of Glasgow, Scotland, UK, July 22-24, 2010. Abstract. NEUROIMAGE, 51 (NRM2010 abstracts of Poster presentations) (2010).
• Volkow N.D., Wang G.-J., Tomasi D., Telang F., Fowler J.S., Pradhan K., Jayne M., Logan J., Goldstein R.Z., Alia-Klein N., Wong C.T.
  Methylphenidate attenuates limbic brain inhibition after cocaine-cues exposure in cocaine abusers.
  PLOS ONE, 5(7):e1150-e1159 (2010).  PubMed
• Wang G.J., Geliebter A., Volkow N.D., Telang F.W., Logan J., Jayne M.C., Galanti K., Selig P.A., Han H., Zhu W., Wong C.T., and Fowler J.S.
  Dopamine D4 receptors modulate brain metabolic activity in the prefrontal cortex and cerebellum at rest and in response to methylphenidate.
  Euro.Journal of Neurosci., 32(4):668-676 (2010).   PubMed
• Wang G.-J., Telang F., Logan J., Jayne M., Ma Y., Pradhan K., Wong C.T., and Swanson J.M.
  Cognitive control of drug craving inhibits brain reward regions in cocaine abusers.
  Neuroimage, 49:2536-2543 (2010).  PubMed
• Logan J., Fowler J.S., Dewey S.L., Volkow N.D. and Gatley J.S.
  A consideration of the dopamine D2 receptor monomer-dimer equilibrium and the anomalous binding properties of the dopamine D2 receptor ligand, N-methyl spiperone.
  J. Neural Transm., 108(3):279-286 (2001).  PubMed
• Logan J., Fowler J.S., Volkow N.D., Ding Y.-S., Wang G.-J. and Alexoff D.L.
  A strategy for removing the bias in the graphical analysis method.
  J. Cereb. Blood Flow Metab., 21(3):307-320 (2001).  PubMed
• Logan J., Fowler J.S., Volkow N.D., Wang G.-J., MacGregor R.R., Shea C.
  Reproducibility of repeated measures of deuterium substituted [11C]L-deprenyl ([11C]L-deprenyl D2) binding in the human brain.
  Nucl. Med. Biol., 27(1):43-49 (2000).  PubMed
• Volkow N.D., Logan J., Fowler J.S., Wang G.-J., Gur R.C., Wong C., Felder C., Gatley S.J., Ding Y.-S., Hitzemann R. and Pappas N.
  Decreased brain dopamine activity with age is associated with impairment in frontal and cingulate metabolism.
  Am. J. Psychiatry, 157:75-80 (2000).
• Logan J., Volkow N.D., Fowler J.S., Wang G.-J., Fischman M.W., Foltin R.W., Abumrad N.N., Vitkun S., Gatley S.J., Pappas N., Hitzemann R. and Shea C.E.
  Concentration and Occupancy of Dopamine Transporters in Cocaine Abusers with [ 11 C]-Cocaine and PET.
  Synapse, 27(4):347-356 (1997).  PubMed
• Logan J., Fowler J.S., Volkow N.D., Wolf A.P., Dewey S.L., Schlyer D.J., Macgregor R.R., Hitzmann R., Bendriem B., Gatley S.J., Christman D.R.
  Graphical analysis of reversible radioligand binding from time-activity measurements applied to [N-11C-methyl-(-)-cocaine PET studies in human subjects.
  J. Cereb. Blood Flow Metab., 10:740-747 (1990).  PubMed