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Louis A. Peña - Figure 1

Endothelial cells (LEL-TRITC)

Apoptosis (TUNEL-DAB)

Composite

Radiation-induced apoptosis of an endothelial cell in the adult mouse brain. In this histological section a red staining cell body (indicating an endothelial cell) co-localized with a brown staining nucleus (indicating apoptotic death) at 12 hours after irradiation. The amount of apoptosis is reduced 2-4 fold by pretreatment with bFGF.