General Information

Top of Page

Louis A. Peña - Figure 2

Increased survival in mice exposed to lethal doses of gamma-radiation and given single-dose treatment with bFGF or synthetic FGF analogs. Unlike other radioprotectants which must be administered prior to irradiation, the time window for cytokine-mediated radioprotection extends several hours after irradiation. Unlike natural or recombinant protein cytokines/growth factors, synthetic FGF analogs survive the GI tract and can be administered orally.