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David Schlyer

Biosciences Chairman

Research Interests

  • Cyclotron targetry development; nuclear cross-section measurement; Biomedical imaging technology

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Selected Publications

  • Beebe-Wang, J., Vaska, P., Dilmanian, F. A., Peggs, S. G., and Schlyer, D. J. Verifying radiation treatment in proton therapy via PET imaging of the induced positron-emitters. Theory of Heavy Ion Collision Physics in Hadron Therapy: Advances in Quantum Chemistry, D. Belkic, Editor, Vol. 65, Chapter 5, pp. 111-127, Elsevier Academic Press, Inc., San Diego, CA (2013). 
  • Sharma R., Xu Y., Kim S.W., Schueller M.J., Alexoff D., Smith S.D., Wang W., and Schlyer D. Carbon-11 radiolabeling of iron-oxide nanoparticles for dual-modality PET/MR imaging. Nanoscale, 5(16):7476-7483 (2013). 
  • Kinsella K., Schlyer D.J., Fowler J.S., Martinez R.J., and Sobecky P.A. Evaluation of positron emission tomography as a method to visualize subsurface microbial processes. J. Hazardous Materials, 213-214:498-501 (2012). 
  • Maramraju S.H., Smith S.D., Rescia S., Stoll S., Budassi M., Vaska P., Woody C., and Schlyer D.J. Electromagnetic interactions in a shielded PET/MRI system for simultaneous PET/MR imaging in 9.4 T: Evaluation and results. IEEE Transactions on Nuclear Science, 59(5):1892-1899 (2012). 
  • Schlyer D.J. and Ruth T.J. Accelerator production of radionuclides. Industrial Accelerators and Their Applications, R. W. Hamm and M. E. Hamm, Editors, Chapter 4, pp. 139-182, World Scientific Publishing Co., Singapore (August, 2012). 
  • Biegon A., Kim S.W., Alexoff D.L., Jayne M., Carter P., Hubbard B., King P., Logan J., Muench L., Pareto D., Schlyer D., Shea C., Telang F., Wang G.J., Xu Y., and Fowler J.S.
    Unique distribution of romatase in the human brain: in vivo studies with PET and [N-methyl-11C]vorozole.
    Synapse, 64(11):801-807 (2010).  PubMed
  • Woody C., Schlyer D., Vaska P., Tomasi D., Solis-Najera S., Rooney W., Pratte J.F., Junnarkar S., Stoll S., Master Z., Purschke M., Park S.J., Southekal S., Kriplani A., Krishnamoorthy S., Maramraju S., O'Connor P. and Radeka V.
    Preliminary studies of a simultaneous PET/MRI scanner based on the RatCAP small animal tomograph.
    Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 571(1-2):102-105 (2007).
  • Woody C., Vaska P. Schlyer D., Pratte J.F., Junnarkar S., Park S.J., Stoll S., Purschke M., Southekal S., Kriplani A., Krishnamoorthy S., Maramraju S., Lee D., Schiffer W., Dewey S., Neill J., Kandasamy A., O'Connor P., Radeka V., Fontaine R. and Lecomte R.
    Initial studies using the RatCAP conscious animal PET tomograph.
    Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 571(1-2):14-17 (2007).
  • Shokouhi S., Vaska P., Schlyer D.J., Stoll S.P., Villanueva A. Jr., Kriplani A. and Woody C.L.
    System performance Simulations of the RatCAP awake rat brain scanner.
    IEEE Transactions on Nuclear Science, Vol. 52 Issue 5 Part 1 :1305-1310 (2005).
  • Woody C.L., Stoll S.P., Schlyer D.J., Shokouhi S., Gerasimov M.
    An Intracerebral Beta Microprobe for Studying Radiotracer Kinetics in Freely Moving Animals.
    IEEE Conference Proceedings, (2000).
  • Firouzbakht M.L., Schlyer D.J., Ferrieri R.A., Wolf A.P. and Fowler J.S.
    Mechanism of Nitrogen-13 Labeled Ammonia Formation in a Cryogenic Water Target.
    Nuclear Medicine and Biology, 26(4):437-441 (1999).  PubMed
  • Firouzbakht M.L. , Schlyer D.J., Gatley S.J. and Wolf A.P.
    A Cryogenic Solid Target for the Production of [ 18 F]Fluoride from Enriched [ 18 O]Carbon Dioxide.
    Int. J. Appl. Radiat. Isot., 44:1081-1084 (1993).