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Gene-Jack Wang

Clinical Research Center and Biomedical Imaging Group Leader

Research Interests

Dr. Wang’s research focuses on the application of PET and functional MRI to the study of various brain disorders. He is interested in using PET to study the neuro-psychiatric mechanisms and manifestations of alcoholism, drug addiction, obesity and eating disorder in humans and in animal models. Using PET, he reported similarity of brain circuits’ disruption in drug addiction and in obesity. Currently, he uses PET to study the effects of drug expectation on the ability of psychostimulants to increase extracellular DA and the relationship to the reinforcing and addictive properties of stimulant drugs in cocaine addicted subjects. His other interests include the study of diet control drug to brain satiety circuit using functional MRI. He has published over 260 peer-reviewed papers on his imaging research. The National Institute of Health and pharmaceutical companies fund his ongoing research.

See Also: PET Research

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Honors

  • The Clubhouse Award – Mental Illness Awareness Day, Clubhouse of Suffolk, Inc. 2002
  • Science and Technology Award – Brookhaven National Laboratory 2004

Selected Publications

  • Alzghoul L., Bortolato M., Delis F., Thanos PK., Darling R.D., Godar S.C., Zhang J., Grant S., Wang G.J., Simpson K.L., Chen K., Volkow N.D., Lin R.C., and Shih J.C.
    Altered cerebellar organization and function in monoamine oxidase A hypomorphic mice.
    Neuropharmacology, 3(7):1208-17. Epub (2012 Dec).  PubMed
  • Delis F., Benveniste H., Xenos M., Grandy D., Wang G.J., Volkow N.D., and Thanos P.K.
    Loss of dopamine D2 receptors induces atrophy in the temporal and parietal cortices and the caudal thalamus of ethanol-consuming mice.
    Alcohol. Clin. Exp. Res., 36(5):815-25. doi: 10.1111/j.1530-0277.2011.01667.x. Epub 2011 Oct 21. (2012 May)  PubMed
  • Michaelides M., Thanos P.K., Kim R., Cho J., Ananth M., Wang G.J., and Volkow N.D.
    PET imaging predicts future body weight and cocaine preference.
    Neuroimage., 59(2):1508-13. Epub 2011 Aug 26. (2012 Jan 16).   PubMed
  • Michaelides M., Thanos P.K., Volkow N.D., and Wang G.J.
    Dopamine-related frontostriatal abnormalities in obesity and binge-eating disorder: emerging evidence for developmental psychopathology.
    Int. Rev. Psychiatry, 24(3):211-218 (2012 Jun).  PubMed
  • Moeller S.J., Tomasi D., Woicik P.A., Maloney T., Alia-Klein N., Honorio J., Telang F., Wang G.J., Wang R., Sinha R., Carise D., Astone-Twerell J., Bolger J., Volkow N.D., and Goldstein R.Z.
    Enhanced midbrain response at 6-month follow-up in cocaine addiction, association with reduced drug-related choice.
    Addict. Biol., 17(6):1013-25. doi: 10.1111/j.1369-1600.2012.00440.x. Epub 2012 Mar 28 (2012 Nov).  PubMed
  • Parvaz M.A., Maloney T., Moeller S.J., Woicik P.A., Alia-Klein N., Telang F., Wang G.J., Squires N.K.,Volkow N.D., and Goldstein R.Z.
    Sensitivity to monetary reward is most severely compromised in recently abstaining cocaine addicted individuals: A cross-sectional ERP study.
    Psychiatry Res., 203(1):75-82. doi: 10.1016/j.pscychresns.2012.01.001. Epub 2012 Jul 26. (2012 Jul 30).  PubMed
  • Shumay E., Fowler J.S., Wang G.J., Logan J., Alia-Klein N., Goldstein R.Z., Maloney T., Wong C., and Volkow N.D.
    Repeat variation in the human PER2 gene as a new genetic marker associated with cocaine addiction and brain dopamine D2 receptor availability.
    Transl. Psychiatry., 2:e86. doi: 10.1038/tp.2012.11. (2012 Mar 6).  PubMed
  • Thanos P.K, Stamos J., Robison L.S., Heyman G., Tucci A., Wang G.J., Robinson J.K., Anderson B.J., and Volkow N.D.
    Daily Treadmill Exercise Attenuates Cocaine Cue-Induced Reinstatement and Cocaine Induced Locomotor Response but Increases Cocaine-Primed Reinstatement.
    Behav Brain Res. doi:pii: S0166-4328(12)00685-7. 10.1016/j.bbr.2012.10.035. [Epub ahead of print](2012 Oct 25).  PubMed
  • Thanos P.K., Subrize M., Delis F., Cooney R.N., Culnan D., Sun M., Wang G.J., Volkow N.D., and Hajnal A.
    Gastric Bypass Increases Ethanol and Water Consumption in Diet-Induced Obese Rats.
    Obes Surg., [Epub ahead of print] (2012 Sep 14).  PubMed
  • Volkow N.D., Kim S.W., Wang G.J., Alexoff D., Logan J., Muench L., Shea C., Telang F., Fowler J.S., Wong C., Benveniste H., and Tomasi D.
    Acute alcohol intoxication decreases glucose metabolism but increases acetate uptake in the human brain.
    Neuroimage, 64C:277-283. doi: 10.1016/j.neuroimage.2012.08.057. [Epub ahead of print] (2012 Aug 28).
  • Volkow N.D., Tomasi D., Wang G.J., Telang F., Fowler J.S., Logan J., Benveniste H., Kim R., Thanos P.K., and Ferré S.
    Evidence that sleep deprivation downregulates dopamine D2R in ventral striatum in the human brain.
    J Neurosci., 32(19):6711-6717 (2012 May 9).  PubMed
  • Volkow N.D., Wang G.J., Fowler J.S., and Tomasi D.
    Addiction circuitry in the human brain.
    Annu. Rev. Pharmacol. Toxicol., 52:321-36. doi: 10.1146/annurev-pharmtox-010611-134625. Epub 2011 Sep 27. Review (2012 Feb 10).  PubMed
  • Volkow N.D., Wang G.J., Fowler J.S., Tomasi D., and Baler R.
    Food and drug reward: overlapping circuits in human obesity and addiction.
    Curr Top Behav Neurosci., 11:1-24 (2012).  PubMed
  • Volkow N.D., Wang G.J., Tomasi D., and Baler R.D.
    Obesity and addiction: neurobiological overlaps.
    Obes Rev., doi: 10.1111/j.1467-789X.2012.01031.x. [Epub ahead of print] (2012 Sep 27).  PubMed
  • Volkow N.D., Wang G.J., Tomasi D., Kollins S.H., Wigal T.L., Newcorn J.H., Telang F.W., Fowler J.S., Logan J., Wong C.T., and Swanson J.M.
    Methylphenidate-elicited dopamine increases in ventral striatum are associated with long-term symptom improvement in adults with attention deficit hyperactivity disorder.
    J. Neurosci., 32(3):841-849 (2012 Jan 18).  PubMed
  • Wang G.J., Smith L., Volkow N.D., Telang F., Logan J., Tomasi D., Wong C.T., Hoffman W., Jayne M., Alia-Klein N., Thanos P., and Fowler J.S.
    Decreased dopamine activity predicts relapse in methamphetamine abusers.
    Mol. Psychiatry.,17(9):918-25. doi: 10.1038/mp.2011.86. Epub 2011 Jul 12 (2012 Sep).  PubMed
  • Volkow N.D., Wang G.J., Tomasi D., and Baler R.D.
    Obesity and addiction: neurobiological overlaps.
    Obes. Rev., doi: 10.1111/j.1467-789X.2012.01031.x. [Epub ahead of print] (2012 Sep 27).  PubMed
  • Thanos P.K., Subrize M., Delis F., Cooney R.N., Culnan D., Sun M., Wang G.J., Volkow N.D., and Hajnal A.
    Gastric Bypass Increases Ethanol and Water Consumption in Diet-Induced Obese Rats.
    Obes. Surg., [Epub ahead of print] (2012 Sep 14).  PubMed
  • Michaelides M., Thanos P.K., Kim R., Cho J., Ananth M., Wang G.J., and Volkow N.D.
    PET imaging predicts future body weight and cocaine preference.
    Neuroimage, 59(2):1508-13. Epub 2011 Aug 26 (2012 Jan 16).  PubMed
  • Michaelides M., Thanos P.K., Volkow N.D., and Wang G.J.
    Dopamine-related frontostriatal abnormalities in obesity and binge-eating disorder: emerging evidence for developmental psychopathology.
    Int. Rev. Psychiatry., 24(3):211-218 (2012 Jun).  PubMed
  • Volkow N.D., Wang G.J., Fowler J.S., Tomasi D., and Baler R.
    Food and drug reward: overlapping circuits in human obesity and addiction.
    Curr. Top Behav. Neurosci.,11:1-24 (2012).  PubMed
  • Alia-Klein N., Parvaz M.A., Woicik P.A., Konova A., Maloney T., Shumay E., Wang R., Telang F., Biegon A., Wang G.-J., Fowler J.S., Tomasi D., Volkow N.D., Goldstein R.Z.
    Gene x Disease Interaction on Orbitofrontal Gray Matter in Cocaine Addiction.
    Arch Gen Psychiatry. 68(3):283-294 (2011).  PubMed
  • Thanos P.K., Bermeo C., Wang G.-J., and Volkow N.D.
    D-Cycloserine Facilitates Extinction of Cocaine Self-Administration in Rats.
    Synapse, doi: 10.1002/syn.20922. (2011)[Epub ahead of print].  PubMed
  • Thanos P.K., Cho J., Kim R., Michaelides M., Primeaux S., Bray G., Wang G.-J., and Volkow, N.D.
    Bromocriptine increased operant responding for high fat food but decreased chow intake in both obesity-prone and resistant rats.
    Behav Brain Res., 217(1):165-170 (2011).  PubMed
  • Thanos P.K., Kim R., Cho J., Michaelides M., Anderson B.J., Primeaux S.D., Bray G.A., Wang G.-J., Robinson J.K., and Volkow N.D.
    Obesity-resistant S5B rats showed great cocaine conditioned place preference than the obesity-prone OM rats.
    Physiology and Behavior., 101:713-718 (2011).
  • Thanos P.K., Gopez V., Delis F., Michaelides M., Grand D.K., Wang G.-J., Kunos G., and Volkow N.D.
    Upregulation of Cannabinoid Type 1 Receptors in Dopamine D2 Receptor Knockout Mice Is Reversed by Chronic Forced Ethanol Consumption.
    Alcohol Clin Exp Res., 35(1):19-27. doi: 10.1111/j.1530-0277.2010.01318.x. (2011).  PubMed
  • Volkow N.D., Wang G.J., and Baler R.D.
    Reward, dopamine and the control of food intake: implications for obesity.
    Trends Cogn. Sci., 15(1):37-46. Epub 2010 Nov 24. Review (2011 Jan).  PubMed
  • Wang G.J., Geliebter A., Volkow N.D., Telang F.W., Logan J., Jayne M.C., Galanti K., Selig P.A., Han H., Zhu W., Wong C.T., and Fowler J.S.
    Enhanced striatal dopamine release during food stimulation in binge eating disorder.
    Obesity (Silver Spring), 19(8):1601-8. doi: 10.1038/oby.2011.27. Epub 2011 Feb 24 (2011 Aug).  PubMed
  • Asensio S., Romero M.J., Romero F.J., Wong C.T., Alia-Klein N., Tomasi D., Wang G.-J., Telang F., Volkow N.D., Goldstein R.Z.
    Striatal dopamine D2 receptor availability predicts the thalamic and medial prefrontal responses to reward in cocaine abusers three years later.
    SYNAPSE, 64(5):397-402 (2010).  PubMed
  • Biegon A., Kim S.W., Alexoff D.L., Jayne M., Carter P., Hubbard B., King P., Logan J., Muench L., Pareto D., Schlyer D., Shea C., Telang F., Wang G.J., Xu Y., and Fowler J.S.
    Unique distribution of aromatase in the human brain: in vivo studies with PET and [N-methyl-11C]vorozole.
    Synapse, 64(11):801-807 (2010).  PubMed
  • Dunning J.P., Parvaz M.A., Hajcak G., Maloney T., Alia-Klein N., Woicik P.A., Telang F., Wang G.-J., Volkow N.D., and Goldstein R.Z.
    Motivated Attention to Cocaine and Emotional Cues in Abstinent and Current Cocaine Users: An ERP Study.
    JOURNAL OF NEUROSCIENCE. 2010. Submitted.
  • Goldstein R.Z., Woicik P.A., Maloney T., Tomasi D., Alia-Klein N., Shan J., Honorio J., Samaras D., Wang R., Telang F., Wang G.J., and Volkow N.D.
    Oral methylphenidate normalizes cingulate activity in cocaine addiction during a salient cognitive task.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA), 107(38):16667-16672 (2010).  PubMed
  • Goldstein R.Z., Woicik P.A., Moeller S.J., Telang F., Jayne M., Wong C., Wang G.-J., Fowler J.S., and Volkow N.D.
    Liking and Wanting of Drug and Non-Drug Rewards in Active Cocaine Users: the STRAP-R Questionnaire.
    Journal of Psychopharmacology, 24(2):257-266 (2010). PubMed
  • Moeller S.J., Maloney T., Parvaz M.A., Alia-Klein N., Woicik P.A., Telang F., Wang G.-J., Volkow N.D., Goldstein R.Z.
    Impaired insight in cocaine addiction: laboratory evidence and effects on cocaine-seeking behavior.
    Brain, 133:1484-1493 (2010).  PubMed
  • Pfaffly J., Michaelides M., Wang G.-J., Pessin J.E., Volkow N.D., and Thanos P.K.
    Leptin Increases Striatal Dopamine D2 Receptor Binding in Leptin-Deficient Obese (ob/ob) Mice.
    Synapse, 64(7):503-510 (2010).  PubMed
  • Thanos P.K., Habibi R., Michaelides M., Patel U.B., Suchland K., Anderson B.J., Robinson J.K., Wang G.J., Grandy D.K., and Volkow N.D.
    Dopamine D4 receptor (D4R) deletion in mice does not affect operant responding for food or cocaine.
    Behav Brain Res., 207(2):508-511 (2010).   PubMed
  • Thanos P.K., Tucci A., Stamos J., Robison L., Wang G.-J., Anderson B.J., and Volkow N.D.
    Chronic Forced Exercise Decreased Cocaine Conditioned Place Preference in Adolescent Male but not Female Lewis Rats.
    Behav Brain Res., 215(1):77-82. (2010). PubMed
  • Tomasi D., Volkow N.D., Wang G.-J., Wang R., Telang F., Caparelli E.C., Wong C.T., Jayne M., and Fowler J.S.
    Oral methylphenidate enhances brain activation and deactivation responses to visual attention and working memory tasks.
    Neuroimage, (2010). Submitted.
  • Volkow N.D., Fowler J.S., Wang G.-J., Shumay E., Telang F., Thanos P., and Alexoff D.
    Distribution and pharmacokinetics of methamphetamine in the human body: clinical implications.
    PLOS ONE, 5(12):e15269 (2010).  PubMed
  • Volkow N.D., Wang G.-J., Fowler J.S., Tomasi D., Telang F., and Baler R.
    Addiction: Decreased reward sensitivity and increased expectation sensitivity conspire to overwhelm the brain’s control circuit.
    Bioessays, 32(9):748-755 (2010).  PubMed
  • Volkow N.D., Wang G.-J., Tomasi D., Telang F., Fowler J.S., Pradhan K., Jayne M., Logan J., Goldstein R.Z., Alia-Klein N., Wong C.T.
    Methylphenidate attenuates limbic brain inhibition after cocaine-cues exposure in cocaine abusers.
    PLOS ONE, 5(7):e1150-e1159 (2010).  PubMed
  • Wang G.J., Geliebter A., Volkow N.D., Telang F.W., Logan J., Jayne M.C., Galanti K., Selig P.A., Han H., Zhu W., Wong C.T., and Fowler J.S.
    Dopamine D4 receptors modulate brain metabolic activity in the prefrontal cortex and cerebellum at rest and in response to methylphenidate.
    Euro.Journal of Neurosci., 32(4):668-676 (2010).   PubMed
  • Wang G.-J., Telang F., Logan J., Jayne M., Ma Y., Pradhan K., Wong C.T., and Swanson J.M.
    Cognitive control of drug craving inhibits brain reward regions in cocaine abusers.
    Neuroimage, 49:2536-2543 (2010).  PubMed
  • Wang G.-J., Volkow N.D., Wigal T., Kollins S.H., Newcorn J.H., Telang T., Logan J., Jayne M., Wong C.T., Han H., Fowler J.S., and Swanson J.M.
    Brain dopamine transporter level in patients with ADHD: an alternative Hypothesis.
    Lancer, (2010). Submitted.
  • Wang R., Wang G.J., Goldstein R.Z., Caparelli E.C., Volkow N.D., Fowler J.S., and Tomasi D.
    Induced magnetic force in human heads exposed to 4 T MRI.
    Journal of Magnetic Resonance Imaging. 31(4):815-820 (2010).  PubMed
  • Xie J., Wang G.-J., Yow L., Cela C.J., Humayun M.S., Wieland J., Lazzi G., and Jadvar H.
    Modeling and Percept of Transcorneal Electrical Stimulation in Humans. IEEE Transactions on Biomedical Engineering. 2010. Submitted.
  • Wang G.J., Volkow N.D., Thanos P.K., and Fowler J.S.
    Imaging of Brain Dopamine Pathways - Implications for Understanding Obesity.
    J. Addict. Med., 3(1):8-18 (2009). PDF File
  • Volkow N.D., Wang G.J., Telang F., Fowler J.S., Goldstein R.Z., Alia-Klein N., Logan J., Wong C., Thanos P.K., Ma Y., and Pradhan K.
    Inverse Association Between BMI and Prefrontal Metabolic Activity in Healthy Adults.
    Obesity (Silver Spring), 17(1):60-65 (2009).  PubMed  PDF File
  • Wang G.J., Volkow N.D., Telang F., Jayne M., Ma Y., Pradhan K., Zhu W., Wong C.T., Thanos P.K., Geliebter A., Biegon A., and Fowler J.S.
    Evidence of gender differences in the ability to inhibit brain activation elicited by food stimulation.
    Proc Natl Acad Sci U S A., 106(4):1249-1254 (2009).  PubMed  PDF File
  • Alia-Klein N., Goldstein R.Z., Kriplani A., Logan J., Tomasi D., Williams B., Telang F., Shumay E., Biegon A., Craig I.W., Henn F., Wang G.-J., Volkow N.D., and Fowler J.S.
    Brain Monoamine Oxidase A Activity Predicts Trait Aggression.
    J Neurosci., 28(19):5099-5104 (2008).  PubMed
  • Alia-Klein N., Kriplani A., Pradhan K., Ma Y., Logan J., Williams B., Craig I.W., Telang F., Tomasi D., Goldstein R., Volkow N.D., Wang G.-J., and Fowler J.S.
    The MAO-A genotype does not modulate resting brain metabolism in adults.
    Psychiatry Res., 164(1):73-76 (2008).  PubMed
  • Chang L., Wang G.-J., Volkow N.D., Ernst T., Telang F., Logan J., and Fowler J.S.
    Decreased brain dopamine transporters contribute to cognitive dysfunction in HIV patients with and without psychostimulant abuse.
    Neuroimage, 42(2):869-878 (2008).
  • Fowler J.S., Volkow N.D., Logan J., Alexoff D., Telang F., Wang G.-J., Wong C.T., Ma Y., Pradhan K., Schlyer D., Jayne M., Hubbard B., Carter P., Warner D., King P., Shea C., Xu Y., and Muench L.
    Fast Uptake and Long-Lasting Binding of Methamphetamine in the Human Brain: Comparison with Cocaine.
    Neuroimage, 43(4):756-763 (2008).  PubMed
  • Goldstein R., Parvas M.A., Maloney T., Alia-Klein N., Woicik P.A., Telang F., Wang G.-J., and Volkow N.D.
    Compromised sensitivity to monetary reward in current cocaine users: an ERP study.
    Psychophysiology, 45(5):705-713 (2008).  PubMed
  • Thanos P.K., Ramalhete R.C., Michaelides M., Piyis Y.K., Wang G.J., and Volkow N.D.
    Leptin receptor deficiency is associated with upregulation of cannabinoid 1 receptors in limbic brain regions.
    Synapse, 62(9):637-642 (2008).  PubMed
  • Thanos P.K., Michaelides M., Benveniste H., Wang G.-J., Volkow N.D.
    The Effects of Cocaine on Regional Brain Glucose Metabolism is Attenuated in Dopamine Transporter Knockout Mice.
    Synapse, 62(5):319-324 (2008).  PubMed
  • Thanos P.K., Michaelides M., Gispert J.D., Pascau J., Soto-Montenegro M.L., Desco M., Wang R., Wang G.J., and Volkow N.D.
    Differences in response to food stimuli in a rat model of obesity: in-vivo assessment of brain glucose metabolism.
    Int. J. Obes. (Lond), 32(7):1171-1179 (2008).  PubMed
  • Thanos P.K., Michaelides M., Ho C.W., Wang G.-J., Newman A.H., Heidbreder C.A., Ashby C.R., Jr., Gardner E.L., and Volkow N.D.
    The Effects of Two Highly Selective Dopamine D3 Receptor Antagonists (SB-277011A and NGB-2904) on food self-administration in a rodent model of obesity.
    Pharmacology Biochemistry Behavior, 89(4):499-507 (2008).  PubMed
  • Thanos P.K., Michaelides M., Piyis Y.K., Wang G.J. and Volkow N.D.
    Food restriction markedly increases dopamine D2 receptor (D2R) in a rat model of obesity as assessed with in-vivo μPET imaging ([11C] raclopride) and in-vitro ([3H] spiperone) autoradiography.
    Synapse, 62(1):50-61 (2008).  PubMed
  • Tomer R., Goldstein R.Z., Wang G.J., Wong C. and Volkow N.D.
    Incentive motivation is associated with striatal dopamine asymmetry.
    Biol. Psychol., 77(1):98-101 (2008).  PubMed
  • Volkow N.D., Fowler J.S., Wang G.-J., Telang F., Logan J., Wong C., Ma J., Pradhan K., Benveniste H., and Swanson J.M.
    Methylphenidate decreased the amount of glucose needed by the brain to perform a cognitive task.
    PLoS ONE, 3(4):e2017 (2008).  PubMed
  • Volkow N.D., Ma Y., Zhu W., Fowler J.S., Li J., Rao M., Mueller K., Pradhan K., Wong C., and Wang G.-J.
    Moderate Doses of Alcohol Disrupt the Functional Organization of the Human Brain.
    Psychiatry Research, 162(3):205-213 (2008).  PubMed
  • Volkow N.D., Wang G.J., Fowler J.S., and Telang F.
    Overlapping neuronal circuits in addiction and obesity: evidence of systems pathology.
    Philos Trans R Soc Lond B Biol Sci., 363(1507):3191-3200 (2008).  PubMed  PDF File
  • Volkow N.D., Wang G.J., Telang F., Fowler J.S., Logan J., Childress A.R., Jayne M., Ma Y. and Wong C.
    Dopamine increases in striatum do not elicit craving in cocaine abusers unless they are coupled with cocaine cues.
    Neuroimage, 39(3):1266-1273 (2008). PubMed
  • Volkow N.D., Wang G.-J., Telang F., Fowler J.S., Logan J., Wong C.T., Ma Y., Pradhan K., Tomasi D., Ferré S., and Jayne M.
    Sleep Deprivation Increases Dopamine in the Human Brain: Association with Cognition and Fatigue.
    Journal of Neuroscience, 28(34):8454-8461 (2008). 
  • Volkow N.D., Wang G.J., Telang F., Fowler J.S., Thanos P.K., Logan J., Alexoff D., Ding Y.S., Wong C., Ma Y., and Pradhan K.
    Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: possible contributing factors.
    Neuroimage, 42(4):1537-1543 (2008).  PubMed   PDF File
  • Wang G.J., Tomasi D., Backus W., Wang R., Telang F., Geliebter A., Korner J., Bauman A., Fowler J.S., Thanos P.K. and Volkow N.D.
    Gastric distention activates satiety circuitry in the human brain.
    Neuroimage, 39(4):1824-1831 (2008).  PubMed
  • Alia-Klein N., Goldstein R.Z., Tomasi D., Zhang L., Fagin-Jones S., Telang F., Wang G.J., Fowler J.S. and Volkow N.D.
    What is in a word? No versus Yes differentially engage the lateral orbitofrontal cortex.
    Emotion, 7(3):649-659 (2007). Erratum in: Emotion. 2007 Nov;7(4):735. PubMed
  • Alia-Klein N., Kriplani A., Logan J., Williams B., Zhu W., Craig I.W., Telang F., Goldstein R., Volkow N.D., Vaska P. and Wang G.J.
    Evidence that brain MAO A activity does not correspond to MAO A genotype in healthy male subjects.
    Biol. Psychiatry, 62(4):355-358 (2007). Epub 2006 Dec 4. PubMed
  • Logan J., Wang G.J., Telang F., Fowler J.S., Alexoff D., Zabroski J., Jayne M., Hubbard B., King P., Carter P., Shea C., Xu Y., Muench L., Schlyer D., Learned-Coughlin S., Cosson V., Volkow N.D. and Ding Y.S.
    Imaging the norepinephrine transporter in humans with (S,S)-[11C]O-methyl reboxetine and PET: problems and progress.
    Nucl Med Biol., 34(6):667-679 (2007). Epub 2007 Jun 8. PubMed
  • Thanos P.K., Michaelides M., Benveniste H., Wang G.J. and Volkow N.D.
    Effects of chronic oral methylphenidate on cocaine self-administration and striatal dopamine D2 receptors in rodents.
    Pharmacol. Biochem. Behav., 87(4):426-433 (2007). PubMed
  • Volkow N.D., Fowler J.S., Wang G.J., Swanson J.M. and Telang F.
    Dopamine in drug abuse and addiction: results of imaging studies and treatment implications.
    Arch Neurol., 64(11):1575-1579 (2007). PubMed
  • Volkow N.D., Wang G.J., Fowler J.S., Telang F., Jayne M. and Wong C.
    Stimulant-induced enhanced sexual desire as a potential contributing factor in HIV transmission.
    Am. J. Psychiatry, 164(1):157-160 (2007). PubMed
  • Volkow N.D., Wang G.J., Newcorn J., Fowler J.S., Telang F., Solanto M.V., Logan J., Wong C., Ma Y., Swanson J.M., Schulz K. and Pradhan K.
    Brain dopamine transporter levels in treatment and drug naïve adults with ADHD.
    Neuroimage, 34(3):1182-1190 (2007). Epub 2006 Nov 27. PubMed
  • Volkow N.D., Wang G.J., Newcorn J., Telang F., Solanto M.V., Fowler J.S., Logan J., Ma Y., Schulz K., Pradhan K., Wong C. and Swanson J.M.
    Depressed dopamine activity in caudate and preliminary evidence of limbic involvement in adults with attention-deficit/hyperactivity disorder.
    Arch.Gen. Psychiatry, 64(8):932-940 (2007). PubMed
  • Volkow N.D., Wang G.J., Telang F., Fowler J.S., Logan J., Jayne M., Ma Y., Pradhan K. and Wong C.
    Profound decreases in dopamine release in striatum in detoxified alcoholics: possible orbitofrontal involvement.
    J. Neurosci., 27(46):12700-12706 (2007). PubMed