David Alexoff

Research Engineer
 

Chemistry Department
Building 555
Brookhaven National Laboratory
P.O. Box 5000
Upton, NY 11973-5000

Phone: (631) 344-4221
FAX:    (631) 344-5815
e-mail: alexoff@bnl.gov

Radiotracer Chemistry and Neuroimaging

Research Interests

Laboratory Automation, Automated PET radiotracer synthesis, Image Analysis, PET


Education & Concurrent Positions

B.S.E.  Duke University, Durham, NC 1981

Chemistry Associate IV, Brookhaven National Laboratory, 1981-1985, Chemistry Associate II, 1985-1995, Chemistry Associate I, 1995-1997, Research Engineer I, 1997-present.


Selected Publications [Medline-Brookhaven Publication Search]

Sellers JP and Alexoff DL: An inexpensive real-time integrator based on a SYM-1 microcomputer for use with high pressure liquid chromatography. Chem., Biomed., Environ. Instrumention . 11(4): 313-320 (1981).

Alexoff DL, Russell JAG, Shiue C-Y, Wolf AP, Fowler JS, MacGregor RR: Modular automation in PET tracer manufacturing: Application of an autosynthesizer to the production of 2-deoxy-2-[ 18 F]fluoro-D-glucose. Int. J. Appl. Radiat. Isot. 37:1045-1061 (1986).

Alexoff D, Schlyer DJ, Wolf AP: Recovery of F-18 fluoride from O-18 water in an electrochemical cell. Int. J. Appl. Radiat. Isot. 40(1): 1-6 (1989).

Alexoff DL: Knowledge-based automated radiopharmaceutical manufacturing for positron emission tomography. In: New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control. A.M. Emran (Ed.), Plenum Press, New York, pp. 339-353 (1991).

Alexoff DL, Fowler JS, Gatley SJ: Removal of the 2.2.2 cryptand (Kryptofix 2.2.2 TM ) from 18 FDG by cation exchange. Int. J. Appl. Radiat. Instrum. A 42:1189-1193 (1991).

Alexoff DL, Casati R, Fowler JS, Wolf AP, Shea C, Schlyer DJ, Shiue C-Y: Ion chromatographic analysis of high specific activity 18 FDG preparations and detection of the chemical impurity 2-deoxy-2-chloro-D-glucose. Appl. Radiat. Isot. 43:1313-1322 (1992).

Alexoff DL, Shea C, Wolf AP, Fowler JS, King P, Gatley SJ and Schlyer DJ: Plasma Input Function Determination for PET Using a Commercial Laboratory Robot. Nucl. Med. Biol. 22(7): (1995).

Alexoff DL, King P, and Gatley SJ: Robotic Control of Whole Blood Processing in Functional Brain Imaging Research. Proceedings of the International Symposium on Laboratory Automation & Robotics (ISLAR) '96, Boston, MA, pp. 820-826 (1996).

 

 

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Last Modified: January 31, 2008