Thin film electronic devices have become an alternative technology to deal with applications where conventional semiconductors materials (e. g. crystalline silicon) cannot fill in for. Such applications involve systems capable of being flexible and transparent, rugged and light weight, large area and costeffective. The development of novel materials and device structures allows the use of thin films in high efficiency solar cells, LEDs, super capacitors, thin film transistors, CMOS circuits, sensors and thin film memories. High quality and uniform thin film semiconductor materials can be achieved using inexpensive solutions-based techniques, however higher quality materials are normally obtained with vacuum-based deposition techniques. Moreover, modeling and simulation of thin film semiconductor devices has become an important resource for circuit and system designers to reach the desired applications. In this talk, we will review current materials and device processing techniques in novel structures for thin film technologies. We will describe how they have been applied in different areas where conventional technologies cannot, including energy harvesting, transparent/flexible circuitry and large area radiation sensing.