1. Center for Functional Nanomaterials Seminar

    "Design of Superlattices of Nucleic Acids-Gold Nanoparticles via DNA Recognition"

    Presented by Monica de la Cruz, Northwestern University

    Tuesday, April 9, 2013, 11 am
    Bldg. 735 - Conf Rm B

    Hosted by: Oleg Gang

    Traditionally, colloidal suspensions have been used to generate BCC and FCC three-dimensional crystals. With multivalent functionalization techniques, the community has been able to design robust structures for materials science applications and optically responsive nanoparticle (NP) assemblies for detection and sensing. In particular, DNA recognition has been used to assemble binary mixtures of spherical nucleotide-Au conjugates into unique superlattices. We have employed molecular dynamics (MD) simulations to identify key elements, such as optimal strength of DNA linkers and percentage of DNA hybridizations, to successfully assemble NPs into a large variety of superlattices. The MD simulations have also elucidated the role that nanostructure coordination plays in the ordering of superlattice assemblies.