Office Contact Info.
Phone: (631) 344-3604
Fax: (631) 344-2358
Mail address: Bldg. 490

Joanna Fowler

Scientist


Telephone: (631) 344-4365
Fax:  (631) 344-7902
e-mail: fowler@bnl.gov

See Also:
Radiotracer Chemistry and Neuroimaging

Research Interests

  • Organic synthesis and neurochemistry; radiotracer synthesis with positron emitters; mechanistic studies relating to the development of radiotracers for positron emission tomography (PET); translational applications of radiotracers to problems in neuroscience; PET studies of neurotransmitter activity, enzyme activity and drug mechanisms.

 Education & Concurrent Positions

  • B.A. University of South Florida, 1964; Ph.D. University of Colorado, 1967
  • Senior Research Associate, University of East Anglia, Norwich, England, 1968
  • Research Associate, Medical Department, Brookhaven National Laboratory, 1969-1971
  • Associate Chemist, Medical Department, BNL, 1971-1974
  • Scientist, continuing, Medical Department, BNL, 1974-1976
  • Chemist, Chemistry Department, BNL, 1976-1983
  • Chemist, with tenure, BNL,1983-1988
  • Senior Chemist, BNL, 1988-present

Selected Publications

  • Fowler J.S., Alia-Klein N., Kriplani A., Logan J., Williams B., Zhu W., Craig I.W., Telang F., Goldstein R., Volkow N.D., Vaska P. and Wang G.J.  Evidence that brain MAO A activity does not correspond to MAO A genotype in healthy male subjects. Biol. Psychiatry., 2007; 62(4):355-8.
  • PubMed
  • Fowler J.S., Kroll C., Ferrieri R., Alexoff D., Logan J., Dewey S.L., Schiffer W., Schlyer D., Carter P., King P., Shea C., Xu Y., Muench L., Benveniste H., Vaska P. and Volkow N.D.   PET studies of d-methamphetamine pharmacokinetics in primates: comparison with l-methamphetamine and ( --)-cocaine. J. Nucl. Med., 2007; 48(10):1724-32.
  • PubMed
  • Fowler J .S., Logan J., Wang G.-J., Volkow N.D., Telang F., Zhu W., Franceschi D., Shea C., Garza V., Xu Y., Ding Y.S., Alexoff D., Warner D., Netusil N., Carter P., Jayne M., King P. and Vaska P.  Comparison of Monoamine Oxidase A In Peripheral Organs In Nonsmokers and Smokers. J. Nucl. Med., 2005; 46(9):1414-1420.
  • PubMed
  • Fowler J.S., Logan J., Wang G.-J., Volkow N.D., Telang F., Zhu W., Franceschi D., Pappas N., Ferrieri R., Shea C., Garza V., Xu Y., Schlyer D., GatleyS.J., Ding Y.-S., Alexoff A., Warner D., Netusil N., Carter P., Jayne M., King P. and Vaska P.
    Low monoamine oxidase B in peripheral organs in smokers.
    Proc. Natl. Acad. Sci., 2003; 100(20):11600-11605.
  • PubMed
  • Fowler S., Wang G.-J., Volkow N.D., Franceschi D., Logan J., Pappas N., Shea C., MacGregor R. and Garza V.   Maintenance of Brain MAO B Inhibition in Smokers after a 12-hour Cigarette Abstinence. J. Am. J. Psychiatry. 2000; 157(11):1864-1866.
  • PubMed
  • Fowler J.S., Volkow N.D., Wang G.J., Ding Y.S. and Dewey S.L.  PET and Drug Research and Development. J. Nucl. Med., 1999; 40(7):1154-1163.
  • PubMed
  • Fowler J.S. and Wolf A.P.  Working Against Time: Rapid Radiotracer Synthesis and Imaging the Human Brain. Accts. Chem. Res., 1997; 30:181-188.
  • Fowler J.S., Volkow N.D., Wang G.-J., Pappas N., Logan J., MacGregor R., Alexoff D., Shea C., Wolf A.P., Warner D., Zezulkova I. and Cilento R.  Inhibition of Monoamine Oxidase B in the Brains of Smokers. Nature, 1996; 379(6567):733-736
  • . PubMed
  • Fowler J.S., Volkow N.D., Wang G.-J., Pappas N., Logan J., Shea C., Alexoff D.L., MacGregor R.R., Schyler D.J., Wolf A.P. and Zelzukova I.  Brain Monoamine Oxidase A Inhibition in Cigarette Smokers. Proc. Natl. Acad. Sci. USA, 1996; 93(24):14065-14069.
  • PubMed
  • Fowler J.S., Wang G.-J., Logan J., Xie S., Volkow N.D., MacGregor R.R., Schlyer D.J., Pappas N., Alexoff D.L., Patlak C. and Wolf A.P.  Selective Reduction of Radiotracer Trapping by Deuterium Substitution: Comparison of [ 11 C]L-Deprenyl and [ 11 C]L-Deprenyl-D2 for MAO B Mapping. J. Nucl. Med., 1995; 36(7): 1255-1262.
  • PubMed

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Last Modified: March 7, 2008
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