Dardo Tomasi, BNL Medical

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Phone: (631) 344-3604
Fax: (631) 344-2358
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Dardo Tomasi

Scientist

Telephone: (631) 344-3640
e-mail: tomasi@bnl.gov

Research Interests

Functional MRI
Dardo Tomasi focuses his research interests on the development of advanced MRI techniques to study the effects of brain diseases and psycho stimulants on brain activation.

Education & Concurrent Positions

M.S. University of Buenos Aires, 1991
Ph.D. University of Buenos Aires, 1996
Assistant Professor, San Martin University, Argentina, 1998-2003
Research Associate, Brookhaven National Laboratory, 2001-2003
Assistant Scientist, Brookhaven National Laboratory, 2003-2005.
Associate Scientist, Brookhaven National Laboratory, 2005-2006.
Scientist, Brookhaven National Laboratory, 2006-2009.
Senior Associate Scientist, National Institutes of Health, 2009-Present.

Selected Publications

Tomasi D.and Volkow N.D.
Gender differences in brain functional connectivity density.
Hum Brain Mapp (in press). PubMed
Tomasi D. and Volkow N.D.
Association between functional connectivity hubs and brain networks.
Cereb Cortex (in press). PubMed
Volkow N.D., Tomasi D., Wang G.J., Fowler J.S., Telang F., Goldstein R.Z., Alia-Klein N., Woicik P., Wong C., Logan J., Millard J., and Alexoff D.
Positive Emotionality is Associated with Baseline Metabolism in Orbitofrontal Cortex and in Regions of the Default Network.
Mol Psychiatry (in press).
Volkow N.D., Wang G.J., Fowler J.S, Tomasi D., and Telang F.
Addiction: Beyond Dopamine Reward Circuitry.
Proc Natl Acad Sci U S A (in press).
Alia-Klein N., Parvaz M.A., Woicik P.A., Konova A.B., Maloney T., Shumay E., Wang R., Telang F., Wang G.J., Fowler J.S., Tomasi D., Volkow N.D., and Goldstein R.Z.
Gene x Disease Interaction on Orbitofrontal Gray Matter in Cocaine Addiction.
Arch Gen Psychiatry, 68:283-294 (2011). PubMed
Tomasi D., Volkow N.D., Wang G.J., Wang R., Telang F., Caparelli E.C., Wong C., Jayne M., and Fowler J.S.
Methylphenidate enhances brain activation and deactivation responses to visual attention and working memory tasks in healthy controls.
Neuroimage, 54:3101-3110 (2011). PubMed
Volkow N.D., Tomasi D., Wang G.J., Fowler J.S., Telang F., Goldstein R.Z., Alia-Klein N., and Wong C.
Reduced Metabolism in Brain “Control Networks” Following Cocaine-Cues Exposure in Female Cocaine Abusers. PLoS ONE, 6:e16573 (2011). PubMed
Volkow N.D., Tomasi D., Wang G.J., Vaska P., Fowler J.S., Telang F., Alexoff D., Logan J., and Wong C.
Effects of Cell Phone Radiofrequency Signal Exposure on Brain Glucose Metabolism.
JAMA, 305:808-813 (2011). PubMed
Asensio S., Romero M.J., Romero F.J., Wong C.T., Alia-Klein N., Tomasi D., Wang G.-J., Telang F., Volkow N.D., Goldstein R.Z.
Striatal dopamine D2 receptor availability predicts the thalamic and medial prefrontal responses to reward in cocaine abusers three years later.
SYNAPSE, 64(5):397-402 (2010). PubMed
Goldstein R.Z., Woicik P.A., Maloney T., Tomasi D., Alia-Klein N., Shan J., Honorio J., Samaras D., Wang R., Telang F., Wang G.J., and Volkow N.D.
Oral methylphenidate normalizes cingulate activity in cocaine addiction during a salient cognitive task.
Proc. Natl. Acad. Sci. (USA), 107(38):16667-16672 (2010). PubMed
Tomasi D. and Volkow N.D.
Functional Connectivity Density Mapping.
Proc. Natl. Acad. Sci. USA, 107:9885-9890 (2010). PubMed
Tomasi D., Volkow N.D., Wang R., Carrillo J., Maloney T., Alia-Klein N., Woicik P.A., Telang F., Goldstein R.Z.
Disrupted Functional Connectivity with Dopaminergic Midbrain in Cocaine Abusers.
PLOS ONE, 5(5):E10815 (2010). PubMed
Volkow N.D., Tomasi D., Wang G.J., Fowler J.S., Telang F., Wang R., Alexoff D., Logan J., Wong C., Pradhan K., Caparelli E.C., Ma Y., and Jayne M.
Effects of low-field magnetic stimulation on brain glucose metabolism.
Neuroimage 51: 623-628 (2010). PubMed
Volkow N.D., Wang G.-J., Fowler J.S., Tomasi D., Telang F., and Baler R.
Addiction: Decreased reward sensitivity and increased expectation sensitivity conspire to overwhelm the brain’s control circuit.
Bioessays, 32(9):748-755 (2010). PubMed
Volkow N.D., Wang G.-J., Tomasi D., Telang F., Fowler J.S., Pradhan K., Jayne M., Logan J., Goldstein R.Z., Alia-Klein N., Wong C.T.
Methylphenidate attenuates limbic brain inhibition after cocaine-cues exposure in cocaine abusers.
PLOS ONE, 5(7):e1150-e1159 (2010). PubMed
Wang R., Wang G.J., Goldstein R.Z., Caparelli E.C., Volkow N.D., Fowler J.S., and Tomasi D.
Induced magnetic force in human heads exposed to 4 T MRI.
Journal of Magnetic Resonance Imaging, 31(4):815-820 (2010). PubMed
Alia-Klein N., Goldstein R.Z., Tomasi D., Woicik P., Moeller S.J., Williams B., Craig I.W., Telang F., Biegon A., Wang G.J., Fowler J.S., and Volkow N.D.
Neural Mechanisms of Anger Regulation as a Function of Genetic Risk for Violence.
Emotion, 9:385-396 (2009). PubMed
Goldstein R.Z., Carrillo J.H., Alia-Klein N., Tomasi D., Maloney T., Woicik P., Wang R.L., Telang F., and Volkow N.D.
Anterior cingulate cortex hypoactivations to an emotionally salient task in cocaine addiction. Proc. Natl. Acad. Sci. USA, 106:9453-9458 (2009). PubMed
Goldstein R.Z., Tomasi D., Alia-Klein N., Carrillo J.H., Maloney T., Woicik P., Wang R.L., Telang F., and Volkow N.D.
Dopaminergic response to drug words in cocaine addiction.
J Neurosci., 29:6001-6006 (2009). PubMed
Mujica-Parodi L.R., Korgaonkar M., Ravindranath B., Greenberg T., Tomasi D., Wagshul M., Ardekani B., Guilfoyle D., Kilpatrick J., Sedler M., and Malaspina D.
Limbic dysregulation is associated with lowered heart rate variability and increased trait anxiety in healthy adults.
Hum Brain Mapp, 30:47-58 (2009). PubMed
Tomasi D., Volkow N.D., Wang R.L., Telang F., Wang G.J., and Fowler J.S.
Dopamine transporters in striatum correlate with deactivation in the default mode network during visuospatial attention.
PLoS ONE, 4:e610 (2009). PubMed
Tomasi D., Wang G.J., Wang R.L., Backus W., Geliebter A., Telang F., Jayne M.C., Wong C., Fowler J.S., and Volkow N.D.
Association of body mass and brain activation during gastric distention: implications for obesity.
PLoS ONE, 4:e6847 (2009). PubMed
Tomasi D., Wang R., Telang F., Boronikolas V., Jayne M.C., Wang G.J., Fowler J.S., and Volkow N.D.
Impairment of attentional networks after 1 night of sleep deprivation.
Cereb Cortex, 19:233-240 (2009). PubMed
Volkow N.D., Tomasi D., Wang G.J., Telang F., Fowler J.S., Wang R.L., Logan J., Wong C., Jayne M., and Swanson J.M.
Hyperstimulation of Striatal D2 Receptors with Sleep Deprivation: Implications for Cognitive Impairment.
Neuroimage, 45:1232-1240 (2009). PubMed
Alia-Klein N., Goldstein R.Z., Kriplani A., Logan J., Tomasi D., Williams B., Telang F., Shumay E., Biegon A., Craig I.W., Henn F., Wang G.-J., Volkow N.D., and Fowler J.S.
Brain monoamine oxidase A activity predicts trait aggression.
J Neurosci 28: 5099-5104 (2008). PubMed
Alia-Klein N., Kriplani A., K. Pradhan, Ma J.Y., Logan J. , Williams B., Craig I.W., Telang F., Tomasi D., Goldstein R.Z., Wang G.J., Volkow N.D., and Fowler J.S.
The MAO A genotype does not modulate resting brain metabolism in adults.
Psychiatry Res., 164:73-76 (2008). PubMed
Caparelli E.C. and Tomasi D.
k-Space spatial low-pass filters can increase signal loss artifacts in echo-planar imaging. Biomed Signal Proc & Control, 3:107-114, 2008. PubMed
Junnarkar S.S., Fried J., Southekal S., Pratte J.-F., O’Connor P., Radeka V., Vaska P., Purschke M., Tomasi D., Woody C., and Fontaine R.
Next generation of real time data acquisition, calibration and control system for the RatCAP scanner.
IEEE Trans. Nuc. Sci., 55:220-224 (2008).
Tomasi D., Chang L., Caparelli E.C., and Ernst T.
Sex differences in sensory gating of the thalamus during auditory interference of visual attention tasks.
Neurosci., 151:1006-1015 (2008). PubMed
Volkow N.D., Wang G.J., Telang F., Fowler J.S., Logan J., Wong C., Ma Y., Pradhan K., Tomasi D., Ferré S., and Jayne M.
Sleep deprivation decreases binding of [11C]raclopride to dopamine D2/D3 receptors in the human brain.
J Neurosci., 28:8454-8461 (2008). PubMed
Wang G.J., Tomasi D., Backus W., Wang R., Telang F., Geliebter A., Korner J., Baumann A., Fowler J.S., and Thanos P.K.
Gastric Distention Activates Satiety Circuitry in the Human Brain.
Neuroimage, 39:1824-1831 (2008). PubMed
Alia-Klein N., Goldstein R.Z., Tomasi D., Zhang L., Telang F., Wang G.-J., Fowler J.S., and Volkow N.D.
What is in a word? No versus Yes differentially engage the lateral orbitofrontal cortex.
Emotion, 7:649-659 (2007). PubMed
Goldstein R.Z., Alia-Klein N., Tomasi D., Zhang L., Cottone L.A., Maloney T., Telang F., Caparelli E.C., Chang L., Ernst T., Samaras D., Squires N.K., and Volkow N.D.
Is decreased prefrontal cortical sensitivity to monetary reward associated with impaired motivation and self-control in cocaine addiction.
Am. J. Psychiatry, 164:43-51 (2007). PubMed
Goldstein R.Z., Tomasi D., Alia-Klein N., Cottone L.A., Zhang L., Telang F., and Volkow N.D.
Subjective sensitivity to monetary gradients is associated with frontolimbic activation to reward in cocaine abusers.
Drug Alcohol Depend., 87:233-240 (2007). PubMed
Goldstein R.Z., Tomasi D., Alia-Klein N., Zhang L., Telang F., and Volkow N.D.
The effect of practice on a sustained attention task in cocaine abusers. Neuroimage, 35:194-206 (2007). PubMed
Goldstein R.Z., Tomasi D., Rajaram S., Cottone L.A., Zhang L., Maloney T., Telang F., Alia-Klein N., and Volkow N.D.
Role of the anterior cingulate and medial orbitofrontal cortex in processing drug cues in cocaine addiction.
Neurosci., 144:1153-1159 (2007). PubMed
Tomasi D., Chang L., Caparelli E.C., and Ernst T.
Different activation patterns for working memory load and visual attention load.
Brain Res., 1132:158-165 (2007). PubMed
Tomasi D.G., and Caparelli E.C.
Macrovascular contribution in activation patterns of working memory. J. Cereb. Blood Flow Metab., 27:33-42 (2007). PubMed
Tomasi D., Goldstein R.Z., Telang F., Maloney T., Alia-Klein N., Caparelli E.C., and Volkow N.D.
Thalamo-cortical dysfunction in cocaine abusers: implications in attention and perception.
Psych. Res. Neuroimaging, 155:189-201 (2007). PubMed
Tomasi D., Goldstein R.Z., Telang F., Maloney T., Alia-Klein N., Caparelli E.C., and Volkow N.D.
Widespread disruption in brain activation patterns to a working memory task during cocaine abstinence.
Brain Res., 1171:83-92 (2007). PubMed
Tomasi D.G., and Wang R.
Induced magnetic field gradients and forces in the human head in MRI.
J Magn Reson Imaging, 26:1340-1345 (2007). PubMed
Woody C., Schlyer D., Vaska P., Tomasi D., Solis-Najera S., Rooney W., Pratte J.F., Junnarkar S., Stoll S., Master Z., Purschke M., Park S.J., Southekal S., Kriplani A., Krishnamoorthy S., Maramraju S., O'Connor P., and Radeka V.
Preliminary studies of a simultaneous PET/MRI scanner based on the RatCAP small animal tomography. Nucl. Inst. Met. Phys. Res., A571:102-105 (2007).
Tomasi D., Chang L., Caparelli E.C., Telang F., and Ernst T.
The human inmmunodeficiency virus reduces network capacity: acoustic noise effect.
Ann. Neurol., 59:419-423 (2006). PubMed
Tomasi D., Ernst T., Caparelli E.C., and Chang L.
Common deactivation patterns during working memory and visual attention tasks: An intra-subject fMRI study at 4 Tesla.
Human Brain Mapp, 27:694-705 (2006). PubMed
Wang G-J., Yang J., Volkow N.D., Telang F., Ma Y., Zhu W., Wong C.T., Tomasi D., and Fowler J.S.
Gastric stimulation activates brain satiety circuit in obese subjects.
Proc. Natl. Acad. Sci. USA, 103:15641-15645 (2006). PubMed
Caparelli E.C., Tomasi D., and Ernst T.
The Effect of Small Rotations on R2* with Echo Planar Imaging. NeuroImage, 24:1164-1169 (2005). PubMed
Foerster B., Tomasi D., and Caparelli E.C.
Magnetic Field Shift due to Mechanical Vibration in Functional MRI.
Magn. Reson. Med., 54:1261-1267 (2005). PubMed
Tomasi D., Caparelli E.C., Chang L., and Ernst T.
fMRI-acoustic noise alters brain activation during working memory tasks.
NeuroImage, 27:377-386 (2005). PubMed
Chang L., Tomasi D., Yakupov R., Lozar C., Arnold S., Caparelli E.C., and Ernst T.
Adaptation of the Attention Network in Human Immunodeficiency Virus Brain Injury.
Ann. Neurol., 56:259-272 (2004). PubMed
Tomasi D., Ernst T., Caparelli E.C., and Chang L.
Practice-induced changes of brain function during visual attention: A parametric fMRI study at 4 Tesla.
NeuroImage, 23:1414-1421 (2004). PubMed
Caparelli E., Tomasi D., Arnold S.,Chang L., and Ernst T.
k-Space Based Motion Detection for fMRI.
NeuroImage, 20(2):1411-1418 (2003). PubMed
Tomasi D.G., and Ernst T.
Echo Planar Imaging at 4T with Minimum Acoustic Noise.
J. Magn. Reson. Imaging, 18:128-30 (2003). PubMed
Tomasi D., Xavier R.F., Foerster B., Panepucci H., Tannus A., and Vidoto E.
Asymmetrical Gradient Coil for Head Imaging.
Magn. Reson. Med., 48(4):707-714 (2002). PubMed
Tomasi D.
Stream Function Optimization for Gradient Coil Design.
Magn. Reson. Med., 45(3):505-512 (2001). PubMed
Caparelli E.C., Tomasi D. and Panepucci H.
Shielded Biplanar Gradient Coil Design.
J. Magn. Reson. Imaging, 9(5):725-731 (1999). PubMed
Tomasi D., Caparelli E.C., H. Panepucci and B. Foerster. Fast Optimization of a Biplanar Gradient Coil Set. J Magn Reson 140: 325-339 (1999). PubMed
Tomasi D. and Panepucci H.
Magnetic Fields Mapping with the Phase Reference Method.
Magn Reson Imaging, 17(1):157-160 (1998). PubMed
Tomasi D., Panepucci H., Vidoto E.L., and Ribeiro Azevedo E.
Use of a Phase Reference for Field Mapping with Amplitude Images at Low Field.
J. Magn. Reson., 131(2):310-314 (1998). PubMed

Last Modified: March 31, 2011
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