New atomic-level “snapshots” reveal how bacteria such as E. coli produce and secrete sticky appendages called pili, which help the microbes attach to and infect human bladder cells.
These molecular-level images — produced at our National Synchrotron Light Source and at the European Synchrotron Radiation Facility in Grenoble, France — unravel a complex choreography of protein-protein interactions that will aid in the design of new antibacterial drugs. Finding ways to interfere with pili formation could help thwart urinary tract infections, which affect millions of women around the world each year.
2011-2630 INT/EXT | Media & Communications Office
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