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Coherent Diffractive Imaging (CDI) for
Biological Applications at NSLS-II
May 17-18, 2010
Brookhaven National Laboratory, Bldg. 703, Large Conference Room
Coherent X-ray Imaging (CXI)
is one of the fastest-growing fields in X-ray sciences and the
development of CXI methods has been burgeoning at several facilities
worldwide. However, a significant challenge
the community faces in the
United States is gaining sufficient access
to dedicated CXI beamlines. The situation will be changed with the advent of
NSLS-II which will be one of the brightest
synchrotron radiation sources in the world. Through bringing together some
of the leading researchers in CXI and potential users, this workshop aims
to:
(i) Identify strong
scientific cases in biology-related fields
for the construction of a dedicated CXI beamline at NSLS-II.
(ii) Identify the best CXI
methodologies that can be realized at NSLS-II for pursuing world-class
research.
(iii) Identify critical
beamline parameters, such as the optimum energy range, the required coherent
flux, monochromaticity and the desired spatial resolutions necessary to open
up new avenues of research.
(vi) Identify the
best sample preparation and data analysis procedures to facilitate CXI of
biological samples at NSLS-II.
Speakers
Thomas Earnest,
Lawrence Berkeley National Lab
/ Xiaojing Huang, Argonne National Laboratory /
Enju Lima, Brookhaven National Laboratory /
Lee Makowski,
Argonne National Laboratory /
John Miao, University of California, Los Angeles /Ian
McNulty, Argonne National Laboratory / Yoshinori Nishino,
Hokkaido University, Japan /
Keith Nugent, University of
Melbourne /
Abbas Ourmazd, University of Wisconsin at Milwaukee /
Jeremy Phillips, UCSF /
David Shapiro, Brookhaven National Laboratory /
Qun Shen, Brookhaven National Laboratory /
Changyong Song, SPring-8 / RIKEN /
Fuyu Tamanoi, University
of California, Los Angeles /
Robert Thorne, Cornell
University /
Gayle Woloschak, Northwestern
University /
Agenda
Monday, May 17
8:00 - 8:30
Continental Breakfast
8:30 - 8:45
Wayne
Hendrickson (Columbia University) - Welcome, Goals
& New Opportunity
Session I: Overview
Chair: Wayne Hendrickson (Columbia University)
8:45
- 9:15
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Qun Shen
(Brookhaven National Laboratory |
NSLS-II Overview and Opportunity for Coherent Diffractive Imaging
(Tentative)
|
| 9:15 - 9:45 |
Keith Nugent (University
of Melbourne) |
CDI, Ptychography and Phase-Diversity |
| 9:45 - 10:15
|
Thomas Earnest (Lawrence
Berkeley National Lab) |
Coherent Diffractive Imaging for Biology and
Bio/Nano-Science |
| 10:15 10:35
|
Coffee Break |
Session II: CDI and Its Biological Applications (I)
Chair: Qun Shen (Brookhaven National Laboratory)
10:35
- 11:05
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John Miao
(University of California, Los Angeles) |
Coherent Diffractive Imaging of Biological
Samples
|
| 11:05 11:35
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Yoshinori
Nishino (Hokkaido University) |
X-ray Diffraction Microscopy for Cellular
Organelles
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| 11:35
- 12:05 |
David Shapiro (Brookhaven
National Lab) |
TBD |
| 12:05 - 13:30
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Lunch |
Session III: Cell and Structural Biology
Chair: Lisa Miller (Brookhaven National Laboratory)
13:30 14:00
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Gayle
Woloschak (Northwestern University) |
Imaging Applications for Detection of TiO2
Nanoparticles in Mammalian Cells and Tissues
|
| 14:00 14:30 |
Lee Makowski (Argonne
National Laboratory) |
In Situ Imaging of Cellulose Crystals |
| 14:30 15:00 |
Fuyu Tamanoi (University
of California, Los Angeles) |
Viewing Yeast Spores in 3D: Future Prospects
|
| 15:00 15:30 |
Jeremy Phillips
(University of California, San Francisco) |
Towards an atomic structure of the Nuclear Pore
Complex |
| 15:30 15:50 |
Coffee Break |
Session IV: CDI and Its Biological Applications (II)
Chair: Keith Nugent (University of Melbourne)
15:50 - 16:20
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Changyong
Song (SPring-8 / RIKEN) |
Biological 3D imaging with Intense, Coherent
X-rays
|
| 16:20 16:50 |
Robert Thorne (Cornell
University) |
Cryopreservation of Biological Samples: From
Art to Science |
| 16:50 17:20 |
Abbas Ourmazd (University
of Wisconsin at Milwaukee) |
Tomography with Random Snapshots of Faint
Non-Stationary Objects |
| 17:20 - 18:00 |
Discussion |
| 18:30 |
Dinner |
Tuesday, May 18
8:00 - 8:30
Continental Breakfast
Session
V: CDI and Its Biological Applications (III)
Chair: Lee Makowski (Argonne National Laboratory)
8:30
- 9:00
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Ian McNulty
(Argonne National Laboratory) |
Coherent Diffractive
Imaging into the Next Decade |
| 9:00 - 9:30 |
Enju Lima (Brookhaven National
Lab) |
Cryogenic X-ray Diffraction Microscopy for Biological Samples
(Tentative)
|
| 9:30 - 10:00 |
Xiaojing Huang (Argonne
National Lab) |
X-ray Diffraction Microscopy on Eukaryotic Cells: Progress and
Challenges
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| 10:00 - 10:20 |
Coffee Break |
Session VI:
Discussion/Planning/Proposal Development
Chair: Thomas Earnest (Lawrence
Berkeley Lab)
| 10:20 - 13:00 |
Working lunch will be provided at noon. |
| |
Identify strong scientific cases in
biology-related fields
for the construction of a dedicated CDI
beamline at NSLS-II.
Identify the best CDI methodologies that can be realized at NSLS-II
for pursuing world-class research.
Identify critical beamline specifications: the optimal energy
range, beamline optics, monochromaticity and desired spatial resolutions
necessary to open up new avenues of research.
Identify the best sample preparation and data analysis procedures
to facilitate CDI of biological samples at NSLS-II.
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Administrative Contact: Lydia Rogers, telephone:
631-344-4746; email: lrogers@bnl.gov
Last Modified: April 2, 2013
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BNL Web Services
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