Trends in Structural Biology
April 28-29, 2011
Brookhaven National Laboratory
Building 510 Large Seminar Room
With the advent of the
NSLS-II, it is a good time to take stock of the current state of the art in
structural biology, and to look forward to what the future will bring. This
meeting is intended to survey current research and develop a perspective on
future themes in structural biology. Discussions will focus both on current
methods and methods currently under development, with the goal of
identifying advances that are most likely to benefit the field.
Speakers
Mario Amzel, Johns
Hopkins / Bert van den Berg, UMASS / Gino Cingolani, Thomas Jefferson U. / Roger Fourme, SOLEIL / James Holton, ALS / Veijo Honkimaki, ESRF / XianPeng Kong,
NYU / Dean Madden, Dartmouth / Enrique Rudino, UNAM / Peter Siddons,
Brookhaven National Lab. /, Gyorgy Snell, Takeda Pharmaceuticals / Yong Tang, Wistar
Inst. /
Michael Wiener, Univ. Virginia / Ji-Fang Zhang, Thomas Jefferson U. / Ming-Ming Zhou, MSSM
Thursday, April 28
Chair: Vivian Stojanoff
| 09:00 -
09:30 |
Opening Remarks |
Qun Shen, BNL (PS) |
| 09:30 -
10:00 |
Protein
Crystallography on Metalloenzmes |
Enrique Rudino, Universidad
Autonoma Nacional de Mexico |
| 10:00 -
10:15 |
Break |
|
Chair: Patrick Loll
| 10:15 -
10:45 |
Peptidylglycine
Hydroxylating Monooxygenase: A Dicopper
Hydroxylase |
Mario Amzel, Johns
Hopkins U. |
| 10:45 -
11:15 |
MX and HPMX Using
Higher Energy Photons: A New Paradigm |
Roger Fourme, SOLEIL |
| 11:15 -
11:30 |
Break |
|
Chair: Saivenkatesh Seetharaman
| 11:30 -
12:00 |
TBA |
Ming-Ming Zhou, Mt. Sinai
School of Medicine |
| 12:00 -
12:30 |
Deciphering the
Mechanism of the Pseudomonas Virulence
Factor Cif |
Dean Madden, Dartmouth
Medical School |
| 12:30 -
1:30 |
Lunch |
|
Chair: Lisa Miller
| 01:30 -
02:00 |
Life Science at the
NSLS II |
Wayne Hendrickson, Columbia
U. |
| 02:00 -
02:30 |
Multisubunit
ATPases: Large, Complex and Essential |
Gino Cingolani, Thomas
Jefferson U. |
| 02:30 -
02:45 |
Break |
|
Chair: Qun Liu
| 02:45 -
03:15 |
How Do Greasy
Molecules Enter Sugar-Coated Bacteria? |
Bert van den Berg, U. Mass.
Med. School |
| 03:15-
03:45 |
structures of
anti-HIV Antibodies and HIV/AIDS Vaccine
Discovery |
Xiangpeng Kong, New York U. |
| 03:45 -
04:00 |
Break |
|
Chair: Jens Birktoft
| 04:00 -
04:30 |
The Optimum
Wavelength for Macromolecular
Crystallography |
James Holton, ALS |
| 04:30 -
05:00 |
Diffraction at High
Photon Energies |
Veijo Honkimaki, ESRF |
| 05:00 -
06:00 |
Discussion leader:Pat Loll |
|
Friday, April 29
Chair: Patrick Loll
| 09:00 - 09:30 |
Membrane Protein
Structural Genomics: An Example, In Progress |
Michael Wiener, U. Virginia |
| 09:30 - 10:00 |
Structural Basis
for Calmodulin as a Versatile Calcium Sensor |
Ji-fang Zhang, Thomas
Jefferson U. |
| 10:00 - 10:15 |
Break |
|
Chair: Enrique Rudino
|
10:15 - 10:45 |
Structural and
Functional Studies of N-Acetyltransferases
that Target Histones and Beyond |
Yong Tang,
Wistar Inst. |
|
10:45 - 11:15 |
Protein Crystallography for Structure Based
Drug Design: The Industrial Perspective |
Gyorgy Snell,
Takeda Pharmaceuticals |
| 11:15 - 11:30 |
Break |
|
Chair: Veijo Honkimaki
| 11:30 - 12:00 |
Trends in X-ray
Detectors |
Peter Siddons, BNL (PS) |
| 12:00 - 1:00 |
Discussion leaders:
Veijo Honkimaki and Gino Cingoglani |
|
Administrative Contact: Lydia Rogers, telephone:
631-344-4746; email: lrogers@bnl.gov

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