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BSA 08-22: Non Thermal Control of DNA-guided Nanoparticle Assemblies

BNL Reference Number: BSA 08-22

Patent Status: Application Number 20110196130 was published on August 11, 2011

Summary

Pre-labeled recognition sequences are able to detect several target species simultaneously with near-single-molecule precision. Detection of antigens, gene sequences, and pathogens can be used for homeland security, personalized medicine, and scientific inquiry.

Description

Novel nanoparticle systems, whose assembly and disassembly can be controlled without heat treatment, are fabricated using a phage single-stranded DNA (ssDNA) binding protein.

Benefits

The technology permits generation of nanoparticle systems which can assemble and disassemble without thermal treatment.

Applications and Industries

Complex DNA-based nanostructures and custom microarrays for molecular diagnostics and drug development; fabrication of a wide array of nanoparticle systems.

Journal Publication
Have Questions?

For more information about this technology, contact Kimberley Elcess, (631) 344-4151.

Tags: diagnostic, DNA, PNA

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