Print Friendly

Categories: advanced materials, nanotechnology

BSA 09-24: Zwitterion-Linker Coatings for Nano-Objects

BNL Reference Number: BSA 09-24

Patent Status: Application Number 20120141797 was published on June 7, 2012

Summary

One method of creating complex structures of nanoparticles is to attach the nanoparticles to DNA strands that are then assembled into the structures. Divalent cations, particularly magnesium ions, are used to ensure the proper formation of DNA scaffolds. Nanoparticles, however, tend to aggregate in the presence of divalent cations, making them unavailable. By attaching zwitterions and linkers to the nanoparticles, complex nanostructures can be assembled onto DNA scaffolds.

Description

Divalent cations, particularly magnesium ions, in concentrations of up to 125 mM, but usually 10 mM, are used to ensure the proper formation of DNA scaffolds. Nanoparticles, however, tend to aggregate in the presence of divalent cations, making them unavailable. By attaching zwitterions and linkers to the nanoparticles, complex nanostructures can be assembled onto DNA scaffolds.

Have Questions?

For more information about this technology, contact Kimberley Elcess, (631) 344-4151.