Category: biotechnology & health
BNL Reference Number: BSA 06-08
Patent Status: Application Number 20080233047 was published on September 25, 2008
Halogenated carboranyl porphyrin compounds have improved solubility, providing enhanced formulation opportunities for these therapeutic and diagnostic compounds.
The invention provides low toxicity halogenated, carborane-containing 5,10,15,20-tetraphenylporphyrin compounds and method of their use in boron neutron capture therapy (BNCT) and photodynamic therapy (PDT).
The halogenated carborane porphyrin compounds provide a potential tumor targeting specificity in boron neutron capture therapy (BNCT) and photodynamic therapy (PDT).
The halogenated, carborane-containing tetraphenylporphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.
For more information about this technology, contact Christine Brakel, (631) 344-7134.
Tags: boron neutron capture, cancer, MRI, PET, PET/MRI