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General Information
Categories: biotechnology & health, environment
BSA 08-01: Single Point Genomic Signature Tags
BNL Reference Number: BSA 08-01
Patent Status: Application Number 20090011511 was published on January 8, 2009
Summary
SP-GST Method - Ribosomal DNA
Determination of the various microbial constituents/microflora present in a sample is facilitated by this technology. By focusing on a specific gene region that is conserved through phylogeny, the various families and species of micro-organisms in the sample mixture is easily and rapidly identified. Population dynamics studies are facilitated by this technology.
Description
Describes a method of generating short genomic signature tags from conserved genetic regions of mibrobial families, such that the individual members of a community can be identifed.
Benefits
The method provides a fast, simple and economical approach to identifying microbial members of a biological community. The microbial population and its dynamics may be used to monitored the health of an individual or an individual environmental location. For example, oral and gastrointestinal flora are useful indicators in human health conditions and likewise, the microbial composition of soil communities is indicative of fertility or depletion and damage to agricultural lands.
Applications and Industries
This technology is specifically adapted for opulation biology, for example, for assessing seasonal variations in a microbial community or in constituents comprising the flora of a biological specimen or biofilms.
Journal Publication
- Use of single-point genome signature tags as a universal tagging method for microbial genome surveys (.pdf)
Have Questions?
For more information about this technology, contact Christine Brakel, (631) 344-7134.
Tags: diagnostic, DNA assay
