Category: biotechnology & health
BNL Reference Number: BSA 11-22
Patent Status: Provisional filed on July 14, 2011
A common problem in genetic engineering of oilseed crops has been the poor germination of seeds carrying the non-native or mutant fatty acid modifying genes. The basis for such poor germination is unknown. This invention addresses poor germination of the transgenic seeds and is useful for increasing the proportion of ricinoleic acid in the seed oils produced from the transgenic plant.
High levels of unusual fatty acids in seeds by introduction of new fatty acid metabolizing enzymes has heretofore resulted in poor germination, and consequently poor oil production. The expression of non-native fatty acid hydroxylase as fusion with the membrane-integrating sequence for translation of integral membrane components (MISTIC sequence) has resulted in considerable enhancement of germination.
The seemingly universal problem of poor germination of oilseeds containing unusual fatty acids and the consequent poor fatty acid production has been addressed by this invention. The expression of the modified fatty acid metabolizing protein as a MISTIC fusion protein results in recovered seed germination and resultant better oil production.
Specialty oilseed crops with enhanced germination could be used as renewable sources of chemical feedstocks.
For more information about this technology, contact Christine Brakel, (631) 344-7134.