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General Information
Category: biotechnology & health
BSA 95-07: NHS-DOTA
BNL Reference Number: BSA 95-07
Patent Status: U.S. Patent Number 5,639,879 was issued on June 6, 1997
Summary
NHS-DOTA
This patent covers the bi-functional chelating reagent NHS DOTA which can be simply used to label macromolecules with chelated metals.
Description
This compound is a bifunctional chelating agent that is useful for tagging macromolecules or other biological compounds with metals, particularly radio-metals. The labeled biological compounds can then be used as tracers for labeling and detection with PET, and SPECT and may also be used for targeted therapy when linked to specific antibodies, for example.
Benefits
The compound may be purchased from an authorized manufacturer or manufactured through the route described in US Patent 5,428,156 (BSA 93-10) under an appropriate license agreement.
Applications and Industries
Companies seeking methods for monitoring therapies and for administering therapeutic radiometals may find this simple compound useful.
Have Questions?
For more information about this technology, contact Christine Brakel, (631) 344-7134.
