Biology Department Seminar
"Modeling Complex Sequence-Function"
Presented by David M. McCandlish, Assistant Professor
Wednesday, November 8, 2017, 11 am
John Dunn Seminar Room, Bldg. 463
Hosted by: Dr. Ian Blaby
Advances in high-throughput genetics now allow the effects of thousands of mutations to be measured simultaneously. How can we understand the complex patterns of genetic interaction revealed by these assays? I will showcase several computational tools to address this problem with applications to protein stability and function, transcription factor binding sites, RNA folding, and molecular evolution