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Understanding DNA Replication

BNL biologists study DNA replication

BNL biologists study DNA replication

Before any cell — healthy or cancerous — can divide, it has to replicate its DNA. So scientists who want to know how normal cells work — and perhaps how to stop abnormal ones — are keen to understand this process. As a step toward that goal, Brookhaven scientists and collaborators from Stony Brook University, Cold Spring Harbor, and MRC Clinical Science Centre, Imperial College, London, have deciphered molecular-level details of the complex choreography by which intricate cellular proteins recognize and bind to DNA to start the replication process. Because DNA replication is so closely tied to cell division, a thorough understanding of the process may lead to new ways to fight the uncontrolled cell division that characterizes cancer. More information

2012-3112  |  INT/EXT  |  Media & Communications Office

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