Friday, July 30, 2010, 11:00 am — John Dunn Seminar Room, Bldg. 463
Charged particle radiation is a powerful tool to help dissect basic cancer development processes, as it can elicit the principal types of genomic alterations that are found in a wide variety of tumors. Charged particle exposures are important considerations for space flight and, increasingly, in cancer therapy. Our work utilizes comparative biology approaches to identify common outcomes from charged particle exposures, with emphases on mutagenesis, aneuploidy, genomic instability and apoptosis. The influence of ionization density, genetic background, and tissue organization on underlying mechanisms and risks will be discussed.
Hosted by: Paul Freimuth
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