Friday, April 8, 2005, 11:00 am — John Dunn Seminar Room, Bldg. 463
A combination of technologies is enabling the cheap and automatic fabrication of long fragments of synthetic DNA. Increasingly, if we can specify the information encoding a genetic system then we can construct a physical instance. As a result, two constraints that impact the design of natural genetic systems are removed. First, engineered genetic systems do not need to descend directly from pre-existing systems. Second, the designs of engineered genetic systems do not need to be able to change or persist across evolutionary timescales. Here, I will discuss (i) our redesign of the genome of a natural biological system, bacteriophage T7, and efforts to construct and test the new genome, (ii) a proposed framework for designing many-component integrated genetic systems, (iii) work that needs doing in support of engineering biology, and (iv) possible consequences of success with respect to current and future biological risks.
Hosted by: F. William Studier
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