Wednesday, April 2, 2008, 11:00 am — John Dunn Seminar Room, Bldg. 463
Solution scattering using x-rays or neutrons can provide valuable information about the structure and dynamics of a protein. Wide-angle x-ray solution scattering (WAXS) can produce information about the secondary and tertiary structures of a protein. It is also very sensitive to structural changes. Small-angle neutron scattering (SANS) can be used to deduce the size and shape of a protein or protein complex. Both methods are particularly useful for membrane proteins where structural information from other methods may be difficult to come by. Furthermore, both are useful for the study of protein dynamics. WAXS can produce information about structural ensembles from which measures of the spatial extent of structural fluctuations can be inferred. Neutron spin-echo spectroscopy (NSE) can be used to determine the time-scale of these fluctuations.
Hosted by: Carl Anderson
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