Monday, May 3, 2010, 1:30 pm — John Dunn Seminar Room, Bldg. 463
Our understanding of microbial cellulase systems has evolved tremendously since the black-box "C1-Cx" theory of Drs. Elwyn Reese and Mary Mandels. This presentation reviews the enabling science that has advanced our understanding and use of lignocellulose as a feedstock for industrial production of ethanol and co-products. The phenotypic observations and experimental results of countless studies in the past 40 years assist the rational design and interpretation of experiments using the tools of modern chemical biology: the "omics" approaches, multi-variant analyses, high throughput screening and testing, protein engineering, numerical modeling, and bioinformatics. A perspective of the past, viewed in the context of today and tomorrow, will be applied toward fully realizing cellulase-cellulose bioconversion in simultaneous-saccharification fermentation (SSF) systems.
Hosted by: Niels van der Lelie
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