Joint Biology Seminar

"Protein Phosphorylation and Signaling Cross-talk in Hormone Effects"

Presented by Hongwei Xue, Director, National Key Laboratory of Plant Molecular Genetics; Director of Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, P. R. China

Tuesday, May 11, 2010, 11:00 am — John Dunn Seminar Room, Bldg. 463

Protein Phosphorylation plays important roles in the perception and transduction of hormone signals. Rice is the main source of food and nutrition for a large proportion of the world's population, and the heading/flowering time of rice is crucial for the rice planting and yield production. Through functional characterization of a rice mutant earlier flowering 1, el1, which flowers early and presents an enhanced GA response, we show that EL1 (a casein kinase I, which plays critical roles in cell division and differentiation through the plant and animal kingdoms) is crucial for GA responses through phosphorylating DELLA protein. EL1 specifically phosphorylates OsGAI/SLR1 to sustain its stability and activity, and negatively regulate GA signaling. This provides informative hints on the GA response control and effects of GA in rice heading, and demonstrates the crucial effects of phosphorylation on the activity and stability of DELLA protein SLR1.
In addition, results on the cross-talk of hormone signaling including BR-IAA, ABA-IAA effects will be presented.

Hosted by: John Shanklin

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