BSA Distinguished Lecture

"Life at the Single Molecule Level"

Presented by Xiaoliang Sunney Xie, Harvard University

Friday, March 4, 2011, 4:00 pm — Berkner Hall Auditorium

In a living cell, gene expression—the transcription of DNA to messenger RNA followed by translation to protein—occurs stochastically, as a consequence of the low copy number of DNA and mRNA molecules involved. Can one monitor these processes in a living cell in real time? How do cells with identical genes exhibit different phenotypes? Recent advances in single-molecule imaging in living bacterial cells allow these questions to be answered at the molecular level in a quantitative manner. It was found that rare events of single molecules can have important biological consequences.

Hosted by: Peter Wanderer

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