Friday, June 8, 2012, 11:00 am — John Dunn Seminar Room, Bldg. 463
A kinase-associated protein (Kae1) is highly conserved across bacteria, archaea and eukaryotes. A highly conserved protein complex containing Kae1, a kinase, and 3 small polypeptides has been identified in yeast and implicated in transcription, telomere maintenance and chromosome segregation. We have found in yeast that this complex is required for a universal modification of tRNA, threonyl carbamoyl adenosine (t6A), which is found in all tRNAs that pair with ANN codons in mRNA. The E. coli ortholog of Kae1, YgjD, is also essential for this modification. It remains to be determined whether all reported defects of mutants of this complex can be attributed to the lack of t6A or whether the complex has multiple functions.
Hosted by: Bill Studier
8248 | INT/EXT | Events Calendar
Not all computers/devices will add this event to your calendar automatically.
A calendar event file named "calendar.ics" will be placed in your downloads location. Depending on how your device/computer is configured, you may have to locate this file and double click on it to add the event to your calendar.
Event dates, times, and locations are subject to change. Event details will not be updated automatically once you add this event to your own calendar. Check the Lab's Events Calendar to ensure that you have the latest event information.