Siyu Wu
CMS Beamline Specialist, Complex scattering, National Synchrotron Light Source II
Brookhaven National Laboratory
National Synchrotron Light Source II
Bldg. 744
P.O. Box 5000
Upton, NY 11973-5000
Dr. Siyu Wu is a Beamline Scientist at the Complex Materials Scattering (CMS) beamline (11-BM) at the National Synchrotron Light Source II (NSLS-II), Brookhaven National Laboratory. His work focuses on supporting user operations and advancing synchrotron-based X-ray scattering techniques—including small- and wide-angle X-ray scattering (SAXS/WAXS) and grazing-incidence methods (GISAXS/GIWAXS)—to study the structure, dynamics, and processing of complex materials across multiple length scales.
Dr. Wu leads the development and maintenance of experimental capabilities for in situ and operando measurements, with emphasis on mechanical deformation, temperature- and humidity-controlled environments, and high-throughput screening. He also plays a key role in implementing beamline automation and intelligent control systems, along with advanced data processing pipelines to support rapid, reproducible, and user-friendly experimentation.
His research interests include processing–structure–property relationships, nanomaterials, soft matter physics, and materials-by-design approaches for advanced manufacturing. Beyond instrumentation development, he collaborates extensively with academic and industrial partners, supports users scientifically, and contributes to proposal review and experiment planning.
Prior to his current role, Dr. Wu was a Postdoctoral Research Associate at NSLS-II, where he worked within the Complex Scattering Program to expand in situ synchrotron capabilities and lead collaborative studies across diverse material systems. He earned his Ph.D. in Chemistry from Temple University, where he investigated nanoparticle alloying and 3D structural evolution using SAXS. He is also proficient in scientific computing and image processing using Python and MATLAB.
Expertise | Education | Appointments | Publications
Expertise
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Synchrotron-based X-ray scattering techniques (SAXS, WAXS, GISAXS, GIWAXS)
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In situ and operando experimental design for studying materials under thermal, mechanical, and environmental stimuli
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Beamline instrumentation and automation
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High-throughput and autonomous workflows for materials characterization
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Structure–property–processing relationships in polymers, nanomaterials, and hybrid materials
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Scientific programming and data analysis using Python, MATLAB, and image processing tools
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Collaborative experiment planning, proposal support, and user training at national user facilities
Education
Ph.D. Temple University (2023)
B.S. University of Science and Technology of China (2017)
Professional Appointments
05/2025-present: Beamline Scientist, NSLS-II, Brookhaven National Laboratory
11/2023-05/2025: Postdoc Research Associate, NSLS-II, Brookhaven National Laboratory
07/2021-09/2022: Visiting Student, APS, Argonne National Laboratory
Selected Publications
- Yang T, Mao J, Xue T, et al (2025) Intermediate States Enable Keratin-like α-To-β Transformations in Strain-Responsive Synthetic Polypeptides. Journal of the American Chemical Society 147:15534–15544. https://doi.org/10.1021/jacs.5c02148
- Wu S, Zuo X, Sun Y (2023) Size-refocusing fitting of small-angle X-ray scattering from polydisperse nanoparticles for shape determination. Journal of Applied Crystallography 56:1739–1750. https://doi.org/10.1107/s160057672300910x
- Wu S, Li M, Sun Y (2019) In Situ Synchrotron X-ray Characterization Shining Light on the Nucleation and Growth Kinetics of Colloidal Nanoparticles. Angewandte Chemie International Edition 58:8987–8995. https://doi.org/10.1002/anie.201900690
- Wu S, Sun Y (2018) In Situ Techniques for Probing Kinetics and Mechanism of Hollowing Nanostructures through Direct Chemical Transformations. Small Methods 2:. https://doi.org/10.1002/smtd.201800165
Brookhaven National Laboratory
National Synchrotron Light Source II
Bldg. 744
P.O. Box 5000
Upton, NY 11973-5000
