How the Five National Quantum Information Science Research Centers Harness the Quantum Revolution

While having their own unique areas of expertise and resources, the NQISRCs are all aligned to the same mission—the advancement of quantum information science

By Hannah Adams, Pete Genzer, Monica Hernandez, Leah Hesla, Scott Jones, Elizabeth Rosenthal, Denise Yazak

Photo of Mingzhao Liu enlarge

Mingzhao Liu explores thin film materials fabrication in a collaboration between Brookhaven National Laboratory and Stony Brook University. These superconducting metal silicides are a promising material for the optimization of quantum computing architecture. (Photo: Brookhaven National Laboratory)

Five National Quantum Information Science Research Centers are leveraging the behavior of nature at the smallest scales to develop technologies for science’s most complex problems. Funded by the U.S. Department of Energy Office of Science, the NQISRCs have been supporting DOE’s mission since 2020 to advance the energy, economic and national security of the United States. By building a national quantum ecosystem and workforce comprising researchers at roughly 70 institutions across the United States, the centers create a rich environment for quantum innovation and co-design.

The NQISRCs integrate state-of-the-art DOE facilities, preeminent talent at national laboratories and U.S. universities, and the enterprising ingenuity of U.S. technology companies.

As a result, the centers are pushing the frontier of what’s possible in quantum computers, sensors, devices, materials and much more.

Each national center is led by a DOE national laboratory:

Leading with science

“Each center is a formidable force for quantum information science on its own, pushing the frontiers of computing, physics, chemistry and materials science to bring transformational new technologies to the nation,” said Q-NEXT Director David Awschalom. “But together, they’re a national powerhouse, elevating quantum science and engineering to special prominence in the U.S. and positioning the country to be a global leader in the field.”

A rapidly emerging field of research, quantum information science examines nature’s quantum properties to build new, powerful ways to process information in areas as varied as medicine, energy and finance. By manipulating matter's most fundamental features, researchers could invent new sensors of unprecedented precision, powerful computers and secure communication networks.

To that end, the centers are working to prototype and evaluate the performance and impact of quantum computers and sensors built using various technological platforms and architectures.

“There are many choices and opportunities to be made in the development of quantum computing and understanding how current devices fail reveals to us the path forward,” said C2QA Director Andrew Houck. “The NQISRCs can tackle this surprisingly hard task because, despite great strides in the field, current quantum computers are still too noisy and prone to error for useful computations.”

Understanding the quantum behavior of materials is crucial for overcoming these noise limitations and for the realization of devices that will offer a quantum advantage. The national labs are uniquely positioned to offer advanced facilities and knowledge that guide the understanding and overcoming of these limitations.

“DOE has invested for years in cutting-edge technologies, tools and facilities at national labs, which offer unique opportunities to enable a leap in performance of quantum devices,” said SQMS Director Anna Grassellino. “We are excited to offer world-leading expertise to make transformational advances in QIS, especially because QIS can help advance our mission of understanding the world at its most fundamental level.”

How the Five National Quantum Information Science Research Centers Harness the Quantum Revolution

Collaborating for quantum innovation

The interdisciplinary teams at the NQISRCs co-design quantum technologies to set the stage for future scientific discoveries. Advances in QIS will bring about society wide benefits, such as new materials and powerful quantum sensors that, when combined with medical imagers, could measure tissue at the individual cell level, bringing far greater sensitivity to today’s magnetic resonance imaging machines.

By understanding what enables and limits different quantum technologies and what tools need to be developed, the co-design effort across the NQISRCs could translate into faster drug and vaccine development, novel materials, improvements in transportation and logistics, and more secure financial networks.

As a national ecosystem, NQISRCs researchers leverage world-class DOE Office of Science user facilities and programs, such as the Advanced Photon Source at Argonne National Laboratory, the Oak Ridge Leadership Computing Facility at Oak Ridge National Laboratory, the Advanced Light Source at Lawrence Berkeley National Laboratory, the National Synchrotron Light Source II at Brookhaven National Laboratory, and the superconducting radio frequency cavity facilities and experience at Fermilab.

“Through the funding of these strategic quantum centers, DOE has given researchers an incredible opportunity to make impactful and world-changing discoveries in QIS,” said QSC Director Travis Humble. “Based on the first two years of operation, there is every reason to believe these centers will make tremendous progress in the coming years in advancing QIS toward real-world innovation. We will see an increasing flow of discovery science through the innovation chain.”

Similarly, laboratory and university scientists can leverage the market-driven technologies developed by their industry partners, such as test beds and simulation tools. Capitalizing on these networks, each center builds a pathway to commercializing quantum technologies and, eventually, bringing them to the public.

Preparing the quantum workforce and engaging with industry

The lasting impact of the NQISRCs co-design efforts for science and technology will depend on a quantum workforce to carry it into the future. All national centers are committed to building a workforce with a focus on diversity, equity and inclusion through institutional degree programs, cooperative training programs with industry and retraining certificate programs. This sets the stage for many more innovations and fundamental science questions to be explored.

“The centers have taken a multipronged approach to train the next generation of QIS scientists and researchers and to create new pipelines for underrepresented groups,” expressed QSA Director Irfan Siddiqi. “We’re all putting forth special efforts to support a diverse quantum workforce in a fast-growing field.”

The QSC at Oak Ridge National Laboratory, for example, held its second annual quantum summer school in May, a forum for sharing QIS topics with high schoolers, college students, postdocs and professionals. The event included panels on workforce development strategies with leading industry representatives as well as networking opportunities for students and staff.

C2QA recently held its second six-week-long quantum computing summer school, QIS101, for undergraduate students this year with a focus on building fundamental and practical skills and growing a diverse quantum workforce. 40% of the participants in C2QA’s summer session were women, and nearly 44% were from communities underrepresented in QIS.

Q-NEXT partners with other quantum institutions to build a more diverse and inclusive quantum workforce through the Open Quantum Initiative, a group led by the Chicago Quantum Exchange. One key effort was the creation of an undergraduate fellowship program for underrepresented, racially minoritized quantum scientists. This summer, fellows worked side-by-side with scientists at collaborating institutions on challenging projects in QIS.

QSA works closely with several regional and international companies with strong records in diversity and inclusion programs. Furthermore, it is partnering with local economic development boards already active in the industry to establish internship and apprenticeship programs and accelerate startups. QSA hosted in 2021 its industry and investor roundtable events, attended by dozens of founders, investors, CEOs, senior scientists and engineers from across the United States and worldwide.

SQMS has announced the recipient of the first Carolyn B. Parker Fellowship, named for Carolyn Beatrice Parker, who was the first African-American woman to earn a postgraduate degree in physics. The center is currently recruiting for a second Parker fellow and is wrapping up the second annual undergraduate internship program as well as the SQMS QIS Summer School, co-hosted by INFN at the Galileo Galilei Institute in Florence, Italy.

On Sept. 14, Brookhaven National Laboratory will host the second NQISRC Virtual Quantum Career Fair. The event aims to make undergraduate, graduate and postdoc communities more aware of the DOE Office of Science’s NQISRCs and the different types of careers in QIS at the centers—from technical to non-STEM careers. The first NQISRC career fair, held in fall 2021, attracted close to 400 participants, with 12% representation from minority-serving institutions.

Advances in quantum information science have the potential to revolutionize research and society. The NQISRCs are at the forefront of this emerging field by developing technologies that go beyond what’s previously possible. Learn more about each center at DOE’s website.

The Co-design Center for Quantum Advantage (C2QA), led by Brookhaven National Laboratory, aims to overcome the limitations of today’s noisy intermediate-scale quantum (NISQ) computer systems to achieve quantum advantage for scientific computations in high-energy, nuclear, chemical, and condensed matter physics. Its technology focus is superconducting microwave circuits and modules for quantum computation and hybrid superconducting/optical devices for quantum communication. The integrated five-year aspirational goal of C2QA is to deliver a factor-of-10 improvement in software optimization, underlying materials and device properties, and quantum error correction, and to ensure these improvements combine to provide a factor-of-1,000 improvement in appropriate metrics for computation and communication. For more information, visit

Q-NEXT is a U.S. Department of Energy National Quantum Information Science Research Center led by Argonne National Laboratory. Q-NEXT brings together world-class researchers from national laboratories, universities and U.S. technology companies with the goal of developing the science and technology to control and distribute quantum information. Q-NEXT collaborators and institutions will create two national foundries for quantum materials and devices, develop networks of sensors and secure communications systems, establish simulation and network testbeds, and train the next-generation quantum-ready workforce to ensure continued U.S. scientific and economic leadership in this rapidly advancing field. For more information, visit

The Quantum Science Center (QSC), a U.S. Department of Energy National Quantum Information Science Research Center led by Oak Ridge National Laboratory, performs cutting edge research at national laboratories, universities, and industry partners to overcome key roadblocks in quantum state resilience, controllability, and ultimately the scalability of quantum technologies. QSC researchers are designing materials that enable topological quantum computing; implementing new quantum sensors to characterize topological states and detect dark matter; and designing quantum algorithms and simulations to provide a greater understanding of quantum materials, chemistry, and quantum field theories. These innovations enable the QSC to accelerate information processing, explore the previously unmeasurable, and better predict quantum performance across technologies. For more information, visit

The Quantum Systems Accelerator (QSA) is one of the five National Quantum Information Science Research Centers funded by the U.S. Department of Energy Office of Science. Led by Lawrence Berkeley National Laboratory (Berkeley Lab) and with Sandia National Laboratories as lead partner, QSA will catalyze national leadership in quantum information science to co-design the algorithms, quantum devices, and engineering solutions needed to deliver certified quantum advantage in scientific applications. QSA brings together dozens of scientists who are pioneers of many of today’s unique quantum engineering and fabrication capabilities. In addition to industry and academic partners across the world, 15 U.S. institutions are part of QSA: Lawrence Berkeley National Laboratory, Sandia National Laboratories, University of Colorado at Boulder, MIT Lincoln Laboratory, Caltech, Duke University, Harvard University, Massachusetts Institute of Technology, Tufts University, UC Berkeley, University of Maryland, University of New Mexico, University of Southern California, UT Austin, and Canada’s Université de Sherbrooke. For more information, please visit

 The Superconducting Quantum Materials and Systems (SQMS) Center is one of the five DOE National Quantum Information Science Research Centers. Led by Fermilab, SQMS is a collaboration of 23 partner institutions – national labs, academia and industry- working together to bring transformational advances in the field of quantum information science. The Center will leverage Fermilab’s expertise in building complex particle accelerators to engineer multi qubit quantum processor platforms based on state-of-the-art qubits and superconducting technologies. Working hand in hand with embedded industry partners, SQMS will build a quantum computer and new quantum sensors at Fermilab which will open unprecedented computational opportunities. For more information, please visit

Brookhaven National Laboratory is supported by the Office of Science of the U.S. Department of Energy. The Office of Science is the single largest supporter of basic research in the physical sciences in the United States and is working to address some of the most pressing challenges of our time. For more information, visit

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