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Tiffany Victor Lovelace

Chemist, Imaging & Microscopy Program, National Synchrotron Light Source II

Brookhaven National Laboratory

National Synchrotron Light Source II
Bldg. 743, Room 142
P.O. Box 5000
Upton, NY 11973-5000

(631) 344-7450
tvictor@bnl.gov

Tiffany is a bioimaging scientist in the imaging and microscopy program (IMP). She has ~10 years of experience in the application of synchrotron imaging techniques to address questions in biological and environmental science, with an emphasis on metal and metalloprotein distribution in cells and tissues and the inorganic N distribution in plant-fungi symbiotic systems.

Expertise | Research | Education | Publications | Highlights

Expertise

Tiffany was trained as a microscopist specializing in UV-vis microscopy, FTIR-Imaging and X-ray Fluorescence Microscopy. She has expertise in the preparation, preservation, and X-ray microanalysis of biological and environmental samples. In her current role, she provides scientific user support for BER researchers at the imaging and microscopy beamlines at NSLS-II. She currently works on developing X-ray sensitive tags such as Lanthanide Binding Tags (LBTs) to image proteins in cells and tissues using X-ray Fluorescence Microscopy.

Research Activities

Plant-microbe symbiotic systems, trace metal imaging in cells and tissues, X-ray sensitive tags, cryogenic tools for X-ray fluorescence microscopy of biological samples

Education

Ph.D. 2018: Chemistry, Stony Brook University (Stony Brook, NY)

B.Sc. 2012: Chemistry, Grambling State University (Grambling, La)

Selected Publications

Victor TW, O'Toole KH, Easthon LM, et al (2020) Lanthanide-Binding Tags for 3D X-ray Imaging of Proteins in Cells at Nanoscale Resolution. Journal of the American Chemical Society 142:2145–2149. https://doi.org/10.1021/jacs.9b11571
Crooks EJ, Irizarry BA, Ziliox M, et al (2020) Copper stabilizes antiparallel β-sheet fibrils of the amyloid β40 (Aβ40)-Iowa variant. Journal of Biological Chemistry 295:8914–8927. https://doi.org/10.1074/jbc.ra119.011955
Zhu X, Victor TW, Ambi A, et al (2020) Copper accumulation and the effect of chelation treatment on cerebral amyloid angiopathy compared to parenchymal amyloid plaques. Metallomics 12:539–546. https://doi.org/10.1039/c9mt00306a
Victor TW, Easthon LM, Ge M, et al (2018) X-ray Fluorescence Nanotomography of Single Bacteria with a Sub-15 nm Beam. Scientific Reports 8:. https://doi.org/10.1038/s41598-018-31461-y
Victor T, Delpratt N, Cseke SB, et al (2017) Imaging Nutrient Distribution in the Rhizosphere Using FTIR Imaging. Analytical Chemistry 89:4831–4837. https://doi.org/10.1021/acs.analchem.6b04376