Case Center at National Synchrotron Light Source II Receives Resource-Sharing Award

Jennifer Bohon enlarge

Jennifer Bohon, lead beamline scientist, prepares samples at beamline 17-BM.

The Case Center for Synchrotron Biosciences (CSB), located at the National Synchrotron Light Source II (NSLS-II)—a U.S. Department of Energy (DOE) Office of Science User Facility at DOE’s Brookhaven National Laboratory—has been awarded second prize in the 2017 Sharing Research Resources competition, held by the American Association of Medical Colleges (AAMC). Winners were chosen for successfully sharing resources between institutions and campuses, including medical schools, teaching hospitals, and other academic institutions.

For over 20 years, CSB—a partnership between Brookhaven Lab and Case Western Reserve University—has made highly complex and expensive research resources available to thousands of scientists around the world. First at the National Synchrotron Light Source and now at NSLS-II, CSB has supported the construction and operation of multiple experimental stations for studies on the structure and function of biological macromolecules.

Currently at NSLS-II, CSB is the partner user of beamlines 17-ID-1 and 17-ID-2, two powerhouses for crystallography with high-throughput and automated measurements. CSB leads operations at beamline 17-BM, an x-ray footprinting experimental station that offers world-leading capabilities for solution state studies of biological macromolecular structure and dynamics. CSB is also constructing a second endstation at this beamline for absorption spectroscopy on biological systems.

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CSB Director Mark Chance (back left) is pictured with members of CSB and NSLS-II at beamline 17-BM.

“The Sharing Research Resources Award recognizes the partnership that we have with DOE and Brookhaven Lab—there’s a lot of trust, a lot of information sharing, and a focus on delivering the best science to the community,” said Mark Chance, director of CSB. “We have been able to add new resources, scientists, users, and technologies to NSLS-II. Entirely new technologies for x-ray footprinting were invented and developed here at CSB.”

In addition to providing world-class resources for biological studies at NSLS-II, CSB also works to grow the fields of structural biology and biophysics by training the next generation of researchers. In the years to come, CSB plans to work with NSLS-II to improve the user experience by simplifying the proposal system and granting access to multiple beamlines at once.

The Case Center for Synchrotron Biosciences is supported by the National Institutes of Health and the National Science Foundation.

Brookhaven National Laboratory is supported by the Office of Science of the U.S. Department of Energy. The Office of Science is the single largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, please visit

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