Technologies Available for License

2024-007: Fluidics Technology for Efficient Autonomous Synthesis

Invention: 2024-007

For technical and licensing related questions, email tcp@bnl.gov.

Summary

Describes a high-throughput self-driven microfluidic platform for on-the-fly autonomous synthesis of target nanoparticles or other materials. Integrated with in-situ characterization, real-time data processing, and artificial intelligence, the platform can make real-time decisions and plan experiments, enabling efficient and rapid exploration of a vast set of synthetic possibilities. Features of the platform include a modular construction, droplet fluidics design and flow path, and reactor design, allowing for parallel synthesis and adaptability for advanced X-ray and other spectrometric analyses. This platform may provide in-depth insights for wet-chemistry synthesis processes. As a proof-of-concept autonomous synthesis of gold nanoparticles is described where the size distribution of gold nanoparticles is shown to be optimized rapidly and efficiently by performing a minimal number of experiments.