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Synchrotron Techniques & Methods

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Bioimaging

Multimodal imaging from the micro- to nanoscale of elemental abundances and chemical speciation in a wide range of biological materials

The Bioimaging Program at Brookhaven Lab's National Synchrotron Light Source II (NSLS-II) offers a wide range of imaging and spectroscopic microscopy tools for the structural and chemical analysis of biological materials from the micro- to the nanoscale. The beamlines in this program specialize in the study of natural materials in plant, environmental, climate, planetary, and sustainability sciences.

Program Beamlines

4-BM XFM

X-ray Fluorescence Microprobe

The XFM beamline offers scientists unique and versatile tools for characterizing elemental abundances and chemical speciation in heterogeneous materials. XFM spans a broad energy range and is designed for multimodal and mesoscale imaging, as well as spatially-resolved spectroscopy in diverse scientific fields, including catalysis and energy sciences as well as biology, environmental sciences and energy sciences.

16-BM QCT

Quantitative Cellular Tomography

The QCT beamline will provide the researchers with a high-throughput analytical approach of imaging frozen hydrated intact cells. Equipped with a cryo-light microscope, the beamline will also have built-in capability of correlation on subcellular morphology and functionality. QCT supports a wide variety of research areas including molecular environmental science, plant and soil sciences, climate, earth and planetary sciences, and life and biological sciences.

BioImaging Core (BIC) of NSLS-II/CBMS is responsible for an offline X-ray Fluorescence Imaging station calledĀ AttoMap-310 (Sigray Inc.). AttoMap covers a broad range of energies (5 source targets) for sensitivity to both light (eg P) and heavy elements (eg U) with spatial resolutions ranging from 5 to 15 microns.

Tiffany Victor is a bioimaging scientist that uses synchrotron imaging techniques to address questions in biological and environmental science, with an emphasis on metal and metalloprotein distribution in cells and tissues and the inorganic N distribution in plant-fungi symbiotic systems.

Ryan Tappero, soil chemist and the lead beamline scientist at the X-ray Fluorescence Microscopy (XFM) beamline, captures an image of a manganese nodule from an agricultural soil prepared as petrographic thin section.

Yang Yang is an X-ray nano-imaging scientist with expertise in 2D and 3D X-ray nano-imaging with synchrotron-based techniques and leads the development of the upcoming Quantitative Cellular Tomography (QCT) beamline.

Our Partners

Synchrotron Earth and Environmental Science (SEES) is a NSF-funding consortium whose mission is to advance research and education in synchrotron-based Earth and environmental science to better understand our planet from the atmosphere to the core. SEES support the XFM, XPD, and FIS beamlines at NSLS-II.