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BioCD-2005: Short Course in Circular Dichroism Spectroscopy of Proteins & Nucleic Acids

June 20-24, 2005

Location
Brookhaven National Laboratory

Purpose & Scope of Workshop
To train researchers in use of circular dichroism (CD) spectroscopy for structural and functional characterization of proteins and nucleic acids in solution.

Syllabus
Lectures will include principles of CD and its application to the analysis of the structure of globular proteins, membrane-bound proteins and nucleic acids. Laboratory sessions on sample preparation, calibration and data collection using conventional (cCD) and synchrotron-source (SRCD) spectrometers, web resources for analysis of protein structures and time resolved (stopped-flow) CD. Participants may bring their own samples that (subject to NSLS procedures) may be examined if time permits. Participants are encouraged to bring laptop computers for use in data analysis.

Intended Audience
Graduate, postdoctoral and research scientists interested in using ultraviolet CD spectroscopy to study the structure and conformation of proteins and other biopolymers. Attendance will be limited to approximately 12 participants.

Cost
Participants will be responsible for their own transportation. A registration fee of $400 USD per participant will cover the costs of meals and Residence House (dormitory style) accommodations during the course. Lodging in the Guest House (more like a motel) is $200 USD additional. Other costs associated with the course will be provided by institutional sponsors.

Sponsors
The Biology and National Synchrotron Light Source Departments at Brookhaven National Laboratory, are funded respectively by the Office of Biological and Environmental Research and the Office of Basic Energy Sciences, both units of the Office of Science, U.S. Department of Energy.