General Lab Information

Laboratory for Biomolecular Structure

COVID-19 Research Support: the Department of Energy wants to ensure they are doing everything possible to enable research into the COVID-19 virus and the search for an effective vaccine or other treatment. The new LBMS is now offering a streamlined and expedited rapid access proposal process for groups that require cryo-EM time for projects directly related to COVID-19.

See also: DOE structural biology resources with a list of their basic characteristics and points of contact.

A world leading facility for multiscale bio-imaging

The Laboratory for Biomolecular Structure (LBMS) is a state-of-the-art center for life science imaging located at Brookhaven National Laboratory. The center offers access to state-of-the-art cryo-electron microscopes and laboratory equipment for studies on the building blocks of all living organisms and their behavior.

The next deadline for LBMS proposals and time requests is March 15, 2021.  |   Submission Details

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Sample preparation and more


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'Empire' High-end EM, 'Powell' Screening EM, 'Stonewall' Screening EM



Access to the facility is free of charge and granted through a peer-reviewed proposal process. Currently, the facility only offers access for COVID-19-related research. More details about other modes of access will be shared once the facility begins standard operations.


The center will have two calls for proposals each year. The facility began accepting COVID-19-related research proposals on July 27, 2020.


To schedule your allocated instrument time, please contact:

  • Liguo Wang
    Liguo Wang

    Director of Scientific Operations

    Laboratory of BioMolecular Structure (LBMS)

    (631) 344-7011,

About Us

The mission of the Laboratory for BioMolecular Structure (LBMS) is to accelerate our fundamental understanding about the building blocks of all living organisms and their function. By gaining the fundamental knowledge, LBMS aims to foster faster developments in biotechnology and medicine to meet the Nation’s needs in biofuels and healthcare. LBMS fulfills its mission by offering expertise and access to highly advanced cryo-electron microscopic capabilities to the greater research community.

A Complementary Facility

Our co-location and strong partnership with our neighbor, the National Synchrotron Light Source II (NSLS-II), a U.S. Department of Energy (DOE) Office of Science User Facility, enables our users to take their sciences to the next level by combining cryo-EM capabilities with ultrabright x-ray crystallography, scattering, and imaging.

Learn more about the NSLS-II and its vibrant life science community.


Access to the Laboratory for Biomolecular Structure includes opportunities for training and coaching by our experts. You will find a detailed list and description of training opportunities on the training website once training programs are available.

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LBMS operations are funded by the U.S. Department of Energy’s Biological and Environmental Research program.