This well-attended workshop in the 'New Opportunities' series initiated by Qun Shen, the NSLS-II Experimental Facilities Director, explored structural biology scientific opportunities made possible through the use of micro-beams. It included lectures about studies of difficult-to-crystallize systems and systems for which only small or imperfect crystals could be grown. The impact of using such small beams on mitigating radiation damage of samples was discussed from first principles to experimental verification. Challenges in producing and using such small beams and working with very tiny crystals were reviewed, including experimental methods that require development.
Using the workshop's outcome, the workshop organizers prepared a report, the MX Microbeam White Paper, that guided us in drafting a 2010 beamline development proposal. Earlier, workshop reports have appeared. These are also posted below. Use the 'Agenda' link in the menu bar above to find lecture abstracts and several of the presentations.
The following distinguished scientists have agreed to speak and lead discussions:David Eisenberg (University of California at Los Angeles)
We invite you to learn from the foremost structural biologists using micro-focused x-ray beams and from the most experienced designers of their beamlines about the unique scientific and experimental capabilities at the one-micron scale. We invite you to take part in discussions of these recent developments. We invite you to weigh in on how they may be translated to the design of new crystallography beamlines at NSLS-II in ways that will optimally serve your needs and fully exploit the uniquely small, stable, and brilliant beams expected to become available here by 2014.
This one-day-and-a-half workshop will be held at Brookhaven National Laboratory. On the evening of July 22, an informal reception at the Brookhaven Center will encourage registration and first contacts. The workshop will convene in earnest on Thursday, July 23, and continue through midday Friday with sessions and several discussions. The Thursday evening dinner will feature an after dinner talk that is part of the workshop program and provide opportunities for more in-depth and personal discussions.
The workshop agenda is focused on invited speakers and discussions. However, we welcome relevant poster contributions. Poster boards will be available outside the meeting auditorium during all coffee breaks. We will post abstracts of contributions as well as 8.5 by 11" sized pdf versions of posters on this website.
Please register early using the workshop registration page. The registration fee is a modest $75 and covers breakfast, lunch, and coffee breaks. The cost for dinner on Thursday night - including the after dinner talk - is $50.
The National Synchrotron Light Source II Project
The National Synchrotron Light Source
The Department of Energy OBER
Brookhaven Science Associates
The BNL Biology Department
The Department of Energy BES
The National Institutes of Health NCRR
The National Institutes of Health NIGMS
FMB-Oxford Ltd, Oxford, UK
Bruker ASC, a former ACCEL Instruments Business
Area Detector Systems Corporation